Comparison of the mechanism of action of valproic acid and levetiracetam as histone deacetylase inhibitors in ovarian cancer cells OVCAR-3
2011/03/N/NZ7/01939
Keywords
Descriptors
- NZ7_12: Prewencja chorób człowieka
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 2 – announced on 2011-09-15
- Amount awarded
- 105 000 PLN
- Project start date
- 2012-09-11
- Project end date
- 2013-07-10
- Project duration
- 10 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- aparat do western blotu (do elektroforezy i transferu) Mini-PROTEAN Tetra Cell and Mini Trans-Blot Module firmy BIO-RAD. Cost: 7 461 PLN
Information in the final report
Publication in academic press/journals (1)
-
Valproic acid, but not levetiracetam, selectively decreases HDAC7 and HDAC2 expression in human ovarian cancer cells
- Authors:
- Patrycja Kwiecińska, Anna Wróbel, Erik Taubøll, Ewa Gregoraszczuk.
- Academic press:
- Toxicology Letters (year: 2014, volume: nie dotyczy, pages: nie dotyczy), Publisher: nie dotyczy
- Status:
- Published
- DOI:
- 10.1016/j.toxlet.2013.10.035. – link to the publication
Articles in post-conference publications (1)
-
Comparison of the mechanism of action of valproic acid and levetiracetam as a histone deacetylase inhibitors in the human ovarian cancer cell line OVCAR-3
- Authors:
- Patrycja Kwiecińska, Ewa Ł. Gregoraszczuk
- Conference:
- The 3rd Winter Workshop of the Society for Biology of Reproduction Central and Local Regulations of Reproductive Processes Zakopane, Poland (year: 2013, pages: 35-36), Publisher: nie dotyczy
- Date:
- conference 30.01.-01.02.2013
- Status:
- Published