Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Comparison of the mechanism of action of valproic acid and levetiracetam as histone deacetylase inhibitors in ovarian cancer cells OVCAR-3

2011/03/N/NZ7/01939

Keywords:

valproic acid levetiracetam histone deacetylase inhibitors ovarian cancer

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Patrycja Kwiecińska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 105 000 PLN

Project start date (Y-m-d): 2012-09-11

Project end date (Y-m-d): 2013-07-10

Project duration:: 10 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. aparat do western blotu (do elektroforezy i transferu) Mini-PROTEAN Tetra Cell and Mini Trans-Blot Module firmy BIO-RAD (7 461 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. Valproic acid, but not levetiracetam, selectively decreases HDAC7 and HDAC2 expression in human ovarian cancer cells
    Authors:
    Patrycja Kwiecińska, Anna Wróbel, Erik Taubøll, Ewa Gregoraszczuk.
    Academic press:
    Toxicology Letters (rok: 2014, tom: nie dotyczy, strony: nie dotyczy), Wydawca: nie dotyczy
    Status:
    Published
    DOI:
    10.035. - link to the publication
  1. Comparison of the mechanism of action of valproic acid and levetiracetam as a histone deacetylase inhibitors in the human ovarian cancer cell line OVCAR-3
    Authors:
    Patrycja Kwiecińska, Ewa Ł. Gregoraszczuk
    Conference:
    The 3rd Winter Workshop of the Society for Biology of Reproduction "Central and Local Regulations of Reproductive Processes" Zakopane, Poland (rok: 2013, ), Wydawca: nie dotyczy
    Data:
    konferencja 30.01.-01.02.2013
    Status:
    Published

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