The role of orexin receptor 1 and 2 (OXR1, OXR2) in the regulation of pancreatic beta and alpha cells functions
2011/03/N/NZ4/02965
Keywords
Descriptors
- NZ4_2: Fizjologia
- NZ4_11: Metabolizm
- NZ4_6: Endokrynologia
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Przyrodniczy w Poznaniu, Wydział Hodowli i Biologii Zwierząt
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 2 – announced on 2011-09-15
- Amount awarded
- 269 850 PLN
- Project start date
- 2012-11-19
- Project end date
- 2015-11-18
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Płatkarka lodu SCOTSMAN AF 80 AS. Cost: 17 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
Activation of TRPV4 channel in pancreatic INS-1E beta cells enhances glucose-stimulated insulin secretion via calcium-dependent mechanisms
- Authors:
- Skrzypski M., Kakkassery M., Mergler S., Grötzinger C., Khajavi N., Sassek M., Szczepankiewicz D., Wiedenmann B., Nowak K.W., Strowski M.
- Academic press:
- Febs Letters (year: 2013, volume: 587, pages: 3281-3287), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.febslet.2013.08.025 – link to the publication
-
Glucagon Regulates Orexin A Secretion in Humans and Rodents
- Authors:
- Arafat A. M, Kaczmarek P., Skrzypski M., Pruszyńska-Oszmalek E., Kołodziejski P., Adamidou A., Ruhla S., Szczepankiewicz D., Sassek M., Billert M., Wiedenmann B.,. Pfeiffer A. F.H,. Nowak K. W, Strowski M. Z.
- Academic press:
- Diabetologia (year: 2014, volume: 57, pages: 2108-2116), Publisher: Springer Science+Business Media
- Status:
- Published
- DOI:
- 10.1007/s00125-014-3335-4 – link to the publication
-
Orexin A modulates INS-1E cell proliferation and insulin secretion via extracellular signal-regulated kinase and transient receptor potential channels
- Authors:
- Skrzypski M., Khajavi N., Mergler S., Billert M., Szczepankiewicz M., Wojciechowicz M., Nowak K.W., Strowski M.Z.
- Status:
- Accepted for publication
Articles in post-conference publications (2)
-
Orexin A stimulates INS-1E cell proliferation via ERK1/2-dependent signaling
- Authors:
- Billert M., Skrzypski M., Rogalska K., Kołodziejski P., Strowski M.Z., Nowak K.W.
- Conference:
- Bioopen I Ogólnopolska Konferencja Doktorantów Nauk o Życiu (year: 2015, pages: 182), Publisher: Uniwersytet Łódzki
- Date:
- conference 20-22 kwietnia
- Status:
- Published
- DOI:
- link to the publication
-
Orexin A improves glycemic control and pancreatic beta cells functions in animal model of type 2 diabetes
- Authors:
- M. Skrzypski, P. Kaczmarek, E. Pruszynska-Oszmalek, M. Sassek, P. A. Kolodziejski, M. Kaczmarek, M. Billert, D. Szczepankiewicz, K. Stupiak, P. Maechler, B. Wiedenmann, K.W. Nowak, M.Z. Strowski
- Conference:
- 29th Congress of the Federation of the International Danube Symposia on Diabetes mellitus 9th Congress of Central European Diabetes Association, Jurmala, Latvia (year: 2014, pages: October 2014, 5:315), Publisher: Verlag Kirchheim + Co GmbH
- Date:
- conference 26-28.07.2014
- Status:
- Published