Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Application of olefin metathesis in the chemistry of natural products

2011/02/A/ST5/00459

Keywords:

olefin metathesis ruthenium catalysts stereoselectivity E/Z isomerism polyenes steroids furans molecular rotors

Descriptors:

  • ST5_23:
  • ST5_25:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny, Instytut Chemii

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Morzycki 

Number of co-investigators in the project: 10

Call: MAESTRO 1 - announced on 2011-06-15

Amount awarded: 1 000 000 PLN

Project start date (Y-m-d): 2012-05-31

Project end date (Y-m-d): 2016-05-31

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Pompa strzykawkowa (10 000 PLN)
  2. Reaktor mikrofalowy (40 000 PLN)
  3. Suszarka próżniowa z pompą próżniową (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (15)
  1. Metathesis approach to natural and synthetic retinoids
    Authors:
    Jadwiga Maj, Jacek W. Morzycki, Lucie Rarova, Grzegorz Wasilewski, Tomasz Sawczuk, Agnieszka Wojtkielewicz
    Academic press:
    Chemicke Listy (rok: 2014, tom: 108, strony: s121-s122), Wydawca: Czeskie Towarzystwo Chemiczne
    Status:
    Published
  2. New indenylidene-type metathesis catalysts bearing unsymmetrical N-heterocyclic ligands with mesityl and nitrobenzyl substituents
    Authors:
    Marta Malinowska, Mariana Kozlowska, Agnieszka Hryniewicka, Stanisław Witkowski, Jacek W. Morzycki
    Academic press:
    Monatsh Chem (rok: 2016, tom: 147, strony: 1091-1100), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00706-016-1697-7 - link to the publication
  3. New metathesis catalyst bearing chromanyl moieties at the N-heterocyclic carbene ligand
    Authors:
    Agnieszka Hryniewicka, Szymon Suchodolski, Agnieszka Wojtkielewicz, Jacek W. Morzycki and Stanisław Witkowski
    Academic press:
    Beilstein J. Org. Chem. (rok: 2015, tom: 11, strony: 2795-2804), Wydawca: Beilstein-Institut
    Status:
    Published
    DOI:
    10.3762/bjoc.11.300 - link to the publication
  4. Solid State Characterization of Bridged Steroidal Molecular Rotors: Effect of the Rotator Fluorination on Their Crystallization
    Authors:
    Dorota Czajkowska-Szczykowska, Andrés Aguilar-Granda, Jadwiga Maj, Agnieszka Z. Wilczewska, Stanisław Witkowski, Rosa Santillan, Miguel A. Garcia-Garibay, Jacek W. Morzycki, Braulio Rodríguez-Molina
    Academic press:
    Crystal Growth&Design (rok: 2016, tom: 16, strony: 1599-1605), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.cgd.5b01705 - link to the publication
  5. The synthesis of disteroidal macrocyclic molecular rotors by an RCM approach
    Authors:
    Dorota Czajkowska-Szczykowska, Izabella Jastrzębska, Rosa Santillan, Jacek W. Morzycki
    Academic press:
    Tetrahedron (rok: 2014, tom: 70, strony: 9427-9435), Wydawca: Elsevier
    Status:
    Published
  6. Pd-catalyzed steroid reactions
    Authors:
    Dorota Czajkowska-Szczykowska, Jacek W. Morzycki, Agnieszka Wojtkielewicz
    Academic press:
    Steroids (rok: 2015, tom: 97, strony: 13-44), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.steroids.2014.07.018 - link to the publication
  7. Stereochemistry of ring-opening/cross metathesis reactions of exo- and endo-7-oxabicyclo[2.2.1]hept-5-ene-2-carbonitriles with allyl alcohol and allyl acetate
    Authors:
    Piotr Wałejko, Michał Dąbrowski, Lech Szczepaniak, Jacek W. Morzycki and Stanisław Witkowski
    Academic press:
    Beilstein J. Org. Chem. (rok: 2015, tom: 11, strony: 1893-1901), Wydawca: Beilstein-Institut
    Status:
    Published
    DOI:
    10.3762/bjoc.11.204 - link to the publication
  8. Synthesis of Aromatic Retinoids and Curcuminoids and Evaluation of their Antiproliferative, Antiradical, and Antiinflammatory Activities
    Authors:
    Jacek W. Morzycki, Lucie Rarova, Jiri Gruz, Tomasz Sawczuk, Urszula Kiełczewska, Leszek Siergiejczyk, Agnieszka Wojtkielewicz
    Academic press:
    ChemistryOpen (rok: 2016, tom: 5, strony: 339-350), Wydawca: Wiley-VCH Verlag GmbH & Co
    Status:
    Published
    DOI:
    10.1002/open.201600027 - link to the publication
  9. Macrocyclic molecular rotors with bridged steroidal frameworks
    Authors:
    D. Czajkowska-Szczykowska, B. Rodríguez-Molina, N. E. Magaňa-Vergara, R. Santillan, J. W. Morzycki, M. A. Garcia-Garibay
    Academic press:
    Journal of Organic Chemistry (rok: 2012, tom: 77, strony: 9970-9978), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/jo3020402 - link to the publication
  10. Synteza i zastosowanie nowych katalizatorów metatezy olefin
    Authors:
    Agnieszka Hryniewicka
    Academic press:
    Wiadomości Chemiczne (rok: 2014, tom: 68, strony: 961-980), Wydawca: PTChem
    Status:
    Published
  11. A cross-metathesis approach to the synthesis of new etretinate type retinoids, ethyl retinoate and its 9Z-isomer
    Authors:
    J. Maj, J. W. Morzycki, L. Rárová, G. Wasilewski, A. Wojtkielewicz
    Academic press:
    Tetrahedron Letters (rok: 2012, tom: 53, strony: 5430-5433), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tetlet.2012.07.122 - link to the publication
  12. Synthesis of new unsymmetrical imidazolinium salts with mesityl and nitrophenyl substituents
    Authors:
    Marta Malinowska, Agnieszka Hryniewicka, Stanisław Witkowski, Jacek W. Morzycki
    Academic press:
    Monatsh Chem (rok: 2014, tom: 145, strony: 1653-1661), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00706-014-1248-z - link to the publication
  13. Synthesis, structure and local molecular dynamics for crystalline rotors based on hecogenin/botogenin steroidal frameworks
    Authors:
    Izabella Jastrzebska, Tomasz Pawlak, Rafael Arcos-Ramos, Edwin Florez-Lopez, Norberto Farfán, Dorota Czajkowska-Szczykowska, Jadwiga Maj, Rosa Santillan, Jacek W. Morzycki, Marek J. Potrzebowski
    Academic press:
    ? , Wydawca: ?
    Status:
    Submitted
  14. Karbeny N-hetrorocykliczne - synteza i zastosowanie
    Authors:
    Marta Malinowska, Agnieszka Hryniewicka
    Academic press:
    Wiadomości Chemiczne (rok: 2015, tom: 69, strony: 227-253), Wydawca: Uniwersytet Wrocławski/PTChem
    Status:
    Published
  15. New olefin metathesis catalysts bearing polyether clamp in N-heterocyclic carbenes ligands
    Authors:
    Agnieszka Hryniewicka, Iwona Misztalewska, Dorota Czajkowska-Szczykowska, Zofia Urbańczyk-Lipkowska, Jacek W. Morzycki, Stanisław Witkowski
    Academic press:
    Tetrahedron (rok: 2014, tom: 70, strony: 6810-6816), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tet.2014.07.056 - link to the publication