Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Conformational studies of selected neurohypophyseal hormone analogues in a membrane-mimicking environment

2011/01/N/ST4/05175

Keywords:

neurohypophyseal hormone analogues NMR micelles

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_15: Colloid chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Emilia Lubecka 

Number of co-investigators in the project: 4

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 130 797 PLN

Project start date (Y-m-d): 2011-12-13

Project end date (Y-m-d): 2014-12-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. pH metr (4 000 PLN)
  2. Zestaw komputerowy (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. Potent antidiuretic agonists, deamino-vasopressin and desmopressin, and their inverso analogs: NMR structure and interactions with micellar and liposomic models of cell membrane
    Authors:
    Emilia A. Lubecka,* Emilia Sikorska , Dariusz Sobolewski, Adam Prahl, Jiřina Slaninová, Jerzy Ciarkowski
    Academic press:
    Biopolymers: Peptide Science (rok: 2016, tom: -, strony: -), Wydawca: Wiley Periodicals, Inc., A Wiley Company
    Status:
    Accepted for publication
    DOI:
    10.1002/bip.22825 - link to the publication
  2. Arginine‑, D‑arginine‑vasopressin, and their inverso analogues in micellar and liposomic models of cell membrane: CD, NMR, and molecular dynamics studies
    Authors:
    Emilia A. Lubecka,* Emilia Sikorska, Dariusz Sobolewski, Adam Prahl, Jiřina Slaninová and Jerzy Ciarkowski
    Academic press:
    European Biophysics Journal (rok: 2015, tom: 44, strony: 727-743), Wydawca: Springer International Publishing AG
    Status:
    Published
    DOI:
    10.1007/s00249-015-1071-4 - link to the publication
  3. Conformational studies of neurohypophyseal hormones analogues with glycoconjugates by NMR spectroscopy
    Authors:
    Emilia A. Lubecka,* Emilia Sikorska, Alina Marcinkowska, Jerzy Ciarkowski
    Academic press:
    Journal of Peptide Science (rok: 2014, tom: 20, strony: 406–414), Wydawca: European Peptide Society and John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/psc.2628 - link to the publication
  1. Techniki magnetycznego rezonansu jądrowego w analizie konformacyjnej peptydów i białek
    Authors:
    Emilia A. Lubecka,* Emilia Sikorska
    Conference:
    Wpływ Młodych Naukowców na Osiągnięcia Nauki Polskiej, VI Edycja (rok: 2014, ), Wydawca: CreativeTime
    Data:
    konferencja 25-27.04.2014
    Status:
    Published
  2. Analogi hormonów neuroprzysadkowych
    Authors:
    Emilia A. Lubecka,* Emilia Sikorska
    Conference:
    Wpływ Młodych Naukowców na Osiągnięcia Nauki Polskiej, VI Edycja (rok: 2014, ), Wydawca: CreativeTime
    Data:
    konferencja 25-27.04.2014
    Status:
    Published
  3. Effect of arginine-8 configuration on conformation of vasopressin analogues and their interactions with liposomes
    Authors:
    Emilia A. Lubecka, Emilia Sikorska, Dariusz Sobolewski, Adam Prahl, Jerzy Ciarkowski
    Conference:
    33rd European Peptide Symposium (rok: 2014, ), Wydawca: European Peptide Society
    Data:
    konferencja 31.08-05.09.2014
    Status:
    Published
  4. Vasopressin and vasotocin - NMR studies in a membrane-mimicking environment
    Authors:
    Lubecka EA, Sikorska E, Kasprzykowski F, Sobolewski D, Ciarkowski J
    Conference:
    32th European Peptide Symposium (rok: 2012, ), Wydawca: European Peptide Society
    Data:
    konferencja 02-07.09.2012
    Status:
    Published