Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Analysis of human stem cells transplanted in three dimensional (3D) environment of umbilical cord Wharton's Jelly into injured rat brain.

2011/01/B/NZ4/05728

Keywords:

somatic stem cells Wharton jelly biodegradable scaffolds biofunctional domains brain injury xenotransplantation

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_9: Systems neurobiology
  • NZ4_10: Neuroimaging and computational neuroscience

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Sarnowska 

Number of co-investigators in the project: 8

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 501 000 PLN

Project start date (Y-m-d): 2012-03-27

Project end date (Y-m-d): 2015-09-26

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. autoklaw do sterylizacji narzędzi i sprzętu labolatoryjnego (30 000 PLN)
  2. Inkubator do hodowli komórkowej (33 999 PLN)
  3. komora laminarna (42 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Book publications / chapters in book publications (1)
  1. Bioengineering of neural stem cell niche
    Authors:
    Buzańska L, Zychowicz M, Sarnowska A, Domańska-Janik K.
    Academic press:
    Postepy Biochem. (rok: 2013, tom: 59(2), strony: 175-86), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
  2. Differentiation of glia-committed NG2 cells: the role of factors released from hippocampus and spinal cord.
    Authors:
    Sypecka J, Sarnowska A, Gadomska-Szabłowska I, Lukomska B, Domańska-Janik K.
    Academic press:
    Acta Neurobiol Exp (Wars). (rok: 2013, tom: 73(1), strony: 116-29), Wydawca: Polish Neuroscience Society - PTBUN
    Status:
    Published
  3. Encapsulation of mesenchymal stem cells by bioscaffolds protects cell survival and attenuates neuroinflammatory reaction in injured brain tissue after transplantation.
    Authors:
    Sarnowska A, Jablonska A, Jurga M, Dainiak M, Strojek L, Drela K, Wright K, Tripathi A, Kumar A, Jungvid H, Lukomska B, Forraz N, McGuckin C, Domanska-Janik K.
    Academic press:
    Cell Transplant. (rok: 2013, tom: 22, strony: 67-82), Wydawca: Cognizant Communication Corporation
    Status:
    Published
    DOI:
    10.3727/096368913X672172 - link to the publication
  4. Original article Heterogeneity of local tissue microenvironment influences differentiation of oligodendroglial progenitors
    Authors:
    Sypecka J, Sarnowska A.
    Academic press:
    Folia Neuropathol. (rok: 2013, tom: 51(2), strony: 103-10), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/fn.2013.35952 - link to the publication
  5. The Organotypic Longitudinal Spinal Cord Slice Culture for Stem Cell Study
    Authors:
    Joanna Sypecka, Sylwia Koniusz, Maria Kawalec and Anna Sarnowska
    Academic press:
    Stem Cells International (rok: 2015, tom: -, strony: 10 pages), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2015/471216 - link to the publication
  6. The neuroprotective effect exerted by oligodendroglial progenitors on ischemically impaired hippocampal cells.
    Authors:
    Sypecka J, Sarnowska A.
    Academic press:
    Mol Neurobiol. (rok: 2014, tom: 49(2), strony: 685-701), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-013-8549-9 - link to the publication
  1. Tissue Engineering and Bioengineering
    Authors:
    Anna Sarnowska, Marzena Zychowicz, Lenora Buzanska, Ying Li, Hongyun Huang and Osamu Kano
    Book:
    Neurorestoratology (rok: 2015, tom: 1, strony: 187-212), Wydawca: Nova Science Publishers Inc
    Status:
    Published