Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Evaluation of activity of a new designer Hypercytokine IL-11 (H11) in megakaryopoiesis and thrombopoiesis

2011/01/B/NZ4/05796

Keywords:

hypercytokine IL-11 thrombocytopenia megakaryopoiesis thrombopoiesis

Descriptors:

  • NZ4_17:
  • NZ5_7: Human disease treatment
  • NZ1_9: Biotechnology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Hanna Dams-Kozłowska 

Number of co-investigators in the project: 5

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 354 900 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2015-06-15

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Silk as an innovative biomaterial for cancer therapy.
    Authors:
    Jastrzebska K, Kucharczyk K, Florczak A, Dondajewska E, Mackiewicz A, Dams-Kozlowska H.
    Academic press:
    Rep Pract Oncol Radiother. (rok: 2015, tom: 20(2), strony: 87-98), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.rpor.2014.11.010 - link to the publication
  2. A designer Hyper interleukin 11 (H11) is a biologically active cytokine.
    Authors:
    Dams-Kozlowska H, Gryska K, Kwiatkowska-Borowczyk E, Izycki D, Rose-John S, Mackiewicz A.
    Academic press:
    BMC Biotechnology (rok: 2012, tom: Vol. 12: 8, strony: xx-xx), Wydawca: BioMed Central Ltd. Part of Springer Science+Business Media
    Status:
    Published
    DOI:
    10.1186/1472-6750-12-8 - link to the publication
  3. Designer Cytokine Hyper Interleukin 11 (H11) is a Megakaryopoietic Factor
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Andrzej Mackiewicz
    Academic press:
    International Journal of Medical Sciences (rok: 2013, tom: 10(9), strony: 1157-1165), Wydawca: Ivyspring International Publisher
    Status:
    Published
    DOI:
    10.7150/ijms.5638 - link to the publication
  4. Effects of Designer Hyper-Interleukin 11 (H11) on Hematopoiesis in Myelosuppressed Mice
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Anna Lewandowska, Andrzej Marszalek, Sebastian Adamczyk, Anna Kowalik, Ewa Leporowska, Andrzej Mackiewicz
    Academic press:
    Plos One (rok: 2016, tom: Vol. 11, nr 5, strony: e0154520 [s. 1-19]), Wydawca: Plos
    Status:
    Published
    DOI:
    10.1371/journal.pone.0154520 - link to the publication
  1. Designer Cytokine Hyper Interleukin 11 (H11) is a Megakaryopoietic Factor
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska, Katarzyna Gryska, Andrzej Mackiewicz
    Conference:
    3d International Conference of Immunotherapy and Immunomonitoring (CITIM) (rok: 2013, ), Wydawca: cancerITIM
    Data:
    konferencja 22-25.04.13
    Status:
    Published
  2. Hyper interleukin 11 (H11) stimulates thrombopoiesis during cancer treatment.
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Andrzej Mackiewicz
    Conference:
    VI Congress of Contemporary Oncology NEXT GENERATION (rok: 2014, ), Wydawca: Termedia, Contemporary Oncology
    Data:
    konferencja 27-29.03.14
    Status:
    Published
    DOI:
    link to the publication
  3. Designer Hyper interleukin 11 (H11) for treatment of chemo/radiotherapy induced thrombocytopenia - in vivo study.
    Authors:
    Hanna Dams-Kozłowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Andrzej Mackiewicz.
    Conference:
    7th International Conference of Contemporary Oncology "Personalized cancer medicine and big data analysis". (rok: 2015, ), Wydawca: Termedia, Contemporary Oncology
    Data:
    konferencja 25-27.03
    Status:
    Published
  4. Designer Hyper interleukin 11 (H11) is a molecule of great potential for treatment of thrombocytopenia.
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska-Borowczyk, Katarzyna Gryska, Andrzej Mackiewicz
    Conference:
    24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (rok: 2012, ), Wydawca: Elsevier, European Jurnal of Cancer,
    Data:
    konferencja 6-9.11.12
    Status:
    Published
  5. Designer Hyper interleukin 11 (H11) is more effective than IL-11 in megakaryopoiesis.
    Authors:
    Hanna Dams-Kozlowska, Eliza Kwiatkowska, Katarzyna Gryska, Andrzej Mackiewicz
    Conference:
    World Biotechnology Congress (rok: 2013, ), Wydawca: Eureca Conferencess
    Data:
    konferencja 3-6.06.13
    Status:
    Published

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