Projects funded by the NCN
The role of HSP70 in the stabilization of p53 mutants in cancer cells
2011/01/N/NZ1/00202
Keywords:
p53 mutations HSP70 MDM2 tumorigenesis degradation aggregation
Descriptors:
- NZ3_1: Cell biology
- NZ4_11: Metabolism
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Międzynarodowy Instytut Biologii Molekularnej i Komórkowej
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 1 - announced on 2011-03-15
Amount awarded: 192 000 PLN
Project start date (Y-m-d): 2011-12-06
Project end date (Y-m-d): 2013-12-05
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (1)
- Molecular Mechanism of Mutant p53 Stabilization: The Role of HSP70 and MDM2Authors:Milena Wiech, Maciej B. Olszewski, Zuzanna Tracz-Gaszewska, Bartosz Wawrzynow, Maciej Zylicz, Alicja ZyliczAcademic press:PLOS ONE (rok: 2012, tom: 7(12), strony: nie dotyczy), Wydawca: PLOS ONEStatus:PublishedDOI:10.1371/journal.pone.0051426 - link to the publication