In vitro and in vivo study of bioavailability and metabolism of selected geniste

In vitro and in vivo study of bioavailability and metabolism of selected genistein derivatives exhibiting antitumor potential

2011/01/N/NZ4/01141

Keywords

Descriptors

NZ4_18: Inne zagadnienia pokrewne
ST4_6: Chemia analityczna

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Politechnika Śląska, Wydział Chemiczny

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Katarzyna Joanna Papaj

Number of co-investigators in the project: 2

Call

PRELUDIUM 1 – announced on 2011-03-15

Amount awarded: 90 000 PLN
Project start date: 2011-12-19
Project end date: 2014-12-18
Project duration: 36 months (the same as in the proposal)
Project status: Project settled

Information in the final report

Publication in academic press/journals (3)

Synthesis and Cytotoxicity of 2,3-Enopyranosyl C-Linked Conjugates of Genistein

Authors:
Wieslaw Szeja, Grzegorz Grynkiewicz, Tadeusz Bieg, Piotr Swierk, Anna Byczek, Katarzyna Papaj, Radosław Kitel, Aleksandra Rusin

Academic press:
Molecules (year: 2014, volume: 19(6), pages: 7072-7093), Publisher: MDPI - Open Access Publishing

Status:
Published

DOI:
10.3390/molecules19067072 – link to the publication
Absorption and metabolism of biologically active genistein derivatives in colon carcinoma cell line (Caco-2)

Authors:
Katarzyna Papaj, Aleksandra Rusin, Wiesław Szeja

Academic press:
Acta Poloniae Pharmaceutica -Drug Research (year: 2014, volume: 71 (6), pages: 1037-1044), Publisher: Polskie Towarzystwo Farmaceutyczne

Status:
Published

DOI:
link to the publication
Genistein Derivatives Regioisomerically Substituted at 7-O- and 4′-O- Have Different Effect on the Cell Cycle

Authors:
A. Byczek, J. Zawisza-Puchalka, A. Gruca, K. Papaj, G. Grynkiewicz, M. Rusin, W. Szeja, A. Rusin

Academic press:
Journal of Chemistry (year: 2013, volume: ID 191563, pages: 12 pages), Publisher: Hindawi Publishing Corporation

Status:
Published

DOI:
10.1155/2013/191563 – link to the publication

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