Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structural brain plasticity driven by extracellular matrix modifiers

2011/01/D/NZ3/00163

Keywords:

brain plasticity extracellular matrix dendritic spines synapse

Descriptors:

  • NZ3_6: Cell neurobiology
  • NZ3_5: Molecular neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jakub Włodarczyk 

Number of co-investigators in the project: 3

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 1 000 000 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2016-12-06

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Shaped Mouse/ Rat Headholder (10 000 PLN)
  2. High NA MPE objectives (20 000 PLN)
  3. Optical table (38 000 PLN)
  4. Physiological - Biological Temperature Controller (7 000 PLN)
  5. Wytrząsarka laboratoryjna.
  6. Aparat do żeli.
  7. Heating pads with stainless steel top plate for small animals (5 000 PLN)
  8. Wirówka laboratoryjna z chłodzeniem i rotorem.
  9. Remote Control / Keypad (10 000 PLN)
  10. Spektrofotometr.
  11. Zestaw pipetorów EASYPET.

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Transient ECM protease activity promotes synaptic plasticity.
    Authors:
    Magnowska M., Gorkiewicz T., Suska A., Wawrzyniak M, Rutkowska-Włodarczyk I, Kaczmarek L, Włodarczyk J.
    Academic press:
    Scientific reports (rok: 2016, tom: 6, strony: 27757), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep27757 - link to the publication
  2. Synaptically released matrix metalloproteinase activity in control of structural plasticity and the cell surface distribution of GluA1-AMPA receptors.
    Authors:
    Szepesi Z., Hosy E., Ruszczycki B., Bijata M., Pyskaty M., Bikbaev A., Heine M., Choquet D., Kaczmarek L., Wlodarczyk J
    Academic press:
    PLoS One (rok: 2014, tom: 9(5), strony: 9(5): e98274.), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0098274 - link to the publication
  3. Sampling Issues in Quantitative Analysis of Dendritic Spines Morphology
    Authors:
    Ruszczycki B., Szepesi Zs., Wilczynski G.M., Bijata M., Kalita K., Kaczmarek L., Wlodarczyk J.
    Academic press:
    BMC Bioinformatics (rok: 2012, tom: 13, strony: 213), Wydawca: BioMed Centra
    Status:
    Published
    DOI:
    10.1186/1471-2105-13-213 - link to the publication
  4. Current microscopic methods for the neural ECM analysis
    Authors:
    Zeug A, Stawarski M, Bieganska K, Korotchenko S, Wlodarczyk J, Dityatev A, Ponimaskin E
    Academic press:
    Progress in brain research (rok: 2014, tom: 2014, strony: 287-312), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/B978-0-444-63486-3.00013-X. - link to the publication
  5. Genetically encoded FRET-based biosensor for imaging MMP-9 activity
    Authors:
    Stawarski M., Rutkowska-Wlodarczyk I., Zeug A., Bijata M., Madej H., Kaczmarek L., Wlodarczyk J
    Academic press:
    Biomaterials (rok: 2014, tom: 35, strony: 1402-1430), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biomaterials.2013.11.033 - link to the publication
  1. Contemporary problems in quantitative image analysis in structural neuronal plasticity
    Authors:
    Ruszczycki B, Bijata M, Walczak A, Wilczynski G and Wlodarczyk J
    Book:
    Advanced Computational Approaches to Biomedical Engineering (rok: 2014, tom: 2, strony: 159-175), Wydawca: Springer
    Status:
    Published
    DOI:
    link to the publication

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