Molecular basis of selective toxicity of N-substituted derivatives of an antifungal antibiotic Nystatin A1
2011/01/N/NZ1/05269
Keywords
Descriptors
- NZ1_2: Biochemia
- NZ1_3: Biofizyka
- NZ1_7: Inżynieria komórkowa
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Politechnika Gdańska, Wydział Chemiczny
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 1
Call
PRELUDIUM 1 – announced on 2011-03-15
- Amount awarded
- 117 000 PLN
- Project start date
- 2011-12-07
- Project end date
- 2014-09-06
- Project duration
- 33 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (1)
-
Novel Nystatin A 1 derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis.
- Authors:
- Joanna Boros-Majewska, Natalia Salewska, Edward Borowski, Sławomir Milewski, Sladjana Malic, Xiao-Qing Wei, Anthony J. Hayes, Melanie J. Wilson, David W. Williams
- Academic press:
- Medical Microbiology and Immunology (year: 2014, volume: 203, pages: 341-355), Publisher: Springer Berlin Heidelberg
- Status:
- Published
- DOI:
- 10.1007/s00430-014-0343-4 – link to the publication
Articles in post-conference publications (3)
-
Does the chemical modification of Nystatin A1 affect the drug's ability to overcome the multidrug resistance of fungi?
- Authors:
- Joanna Boros-Majewska, Natalia Salewska, Maria J. Milewska, Sławomir Milewski, Edward Borowski
- Conference:
- 18th Congress of the International Society for Human and Animal Mycology (year: 2012, pages: 129), Publisher: Wiley-Blackwell
- Date:
- conference 11-15 June
- Status:
- Published
-
An in vitro infection of human leukocytes with Candida albicans to study of host- pathogen interactions.
- Authors:
- Joanna Boros-Majewska, Jakub Karczewski, Sławomir Milewski
- Conference:
- BIO 2014 Congress; 1st Congress of the Polish Biochemistry, Cell Biology, Biophysics and Bioinformatics (year: 2014, pages: 287), Publisher: Polish Biochemical Society and the Committee of Biochemistry and Biophysics Polish Academy of Sciences
- Date:
- conference 9-12 September
- Status:
- Published
-
3D in vitro epithelial tissue model – how to use to study of antifungal agents?
- Authors:
- Joanna Boros-Majewska, Natalia Salewska, Sladjana Malic, Xiao-Qing Wei, Anthony Hayes, David W. Williams, Sławomir Milewski
- Conference:
- 48th Congress of the Polish Biochemical Society (year: 2013, pages: 177), Publisher: Polish Biochemical Society and the Committee of Biochemistry and Biophysics Polish Academy of Sciences
- Date:
- conference 2-5 September
- Status:
- Published