StAR protein trafficking of pro-atherogenic cholesterol hydroperoxides in macrophages
2011/01/B/NZ3/02167
Keywords
Descriptors
- NZ3_1: Biologia komórki
- NZ3_3: Apoptoza
- NZ3_7: Przekaźnictwo sygnału
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Uniwersytet Jagielloński
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 1 – announced on 2011-03-15
- Amount awarded
- 527 500 PLN
- Project start date
- 2011-12-07
- Project end date
- 2014-12-06
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Hood z laminarnym oplywem powietrza. Cost: 60 000 PLN
- Inkubator CO2/O2. Cost: 45 000 PLN
- Mikroskop laboratoryjny.
Information in the final report
Publication in academic press/journals (3)
-
Deleterious Cholesterol Hydroperoxide Trafficking in Steroidogenic Acute Regulatory (StAR) Protein-expressing MA-10 Leydig Cells IMPLICATIONS FOR OXIDATIVE STRESS-IMPAIRED STEROIDOGENESIS
- Authors:
- Korytowski, Witold); Pilat, Anna; Schmitt, JC ; Girotti, AW
- Academic press:
- Journal of Biological Chemistry (year: 2013, volume: Volume: 288, pages: 11509-11519), Publisher: ASBMB
- Status:
- Published
- DOI:
- 10.1074/jbc.M113.452151 – link to the publication
-
Impairment of Macrophage Reverse Cholesterol Transport by StAR-dependent Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress
- Authors:
- W. Korytowski, J.C. Schmitt, K. Wawak, P. Pabisz, D. Sahoo, A. Chadwick, A.W. Girotti
- Academic press:
- Arteriosclerosis, Thrombosis, and Vascular Biology (year: 2015, volume: 35, pages: 2104-2113), Publisher: Lippincott Williams & Wilkins, American Heart Association
- Status:
- Published
- DOI:
- 10.1161/ATVBAH.115.306210 – link to the publication
-
Macrophage Mitochondrial Damage from StAR Transport of 7-Hydroperoxycholesterol: Implications for oxidative stress-impaired reverse cholesterol transport
- Authors:
- Witold Korytowski, Katarzyna Wawak, Pawel Pabisz, Jared C. Schmitt, Albert W. Girotti
- Academic press:
- FEBS Letters (year: 2014, volume: 588, pages: 65-70), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.febslet.2013.10.051 – link to the publication
Articles in post-conference publications (1)
-
Impairment of Macrophage Reverse Cholesterol Transport by StAR-Dependent Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress, , invited talk
- Authors:
- Korytowski W, Schmitt J, Wawak K, Pabisz P, Girotti A,
- Conference:
- 21st Ann Meet SFRBM, Seattle, WA (year: 2014, pages: S48), Publisher: Free Rad. Biol. Med. Vol.76, 2014, p. S48, Elsevier
- Date:
- conference Nov 19-23, 2014
- Status:
- Published
- DOI:
- link to the publication
Book publications / chapters in book publications (2)
-
GENERATION AND REACTIVITY OF LIPID HYDROPEROXIDES
- Authors:
- AW Girotti and W. Korytowski
- Book:
- The chemistry of peroxides (year: 2014, volume: Vol 3, pages: 747-769), Publisher: JOHN WILEY and SONS; Liebman & Greer
- Status:
- Published
-
Reactions of Singlet Oxygen with Membrane Lipids: Lipid Hydroperoxide Generation, Translocation, Reductive Turnover, and Signaling Activity
- Authors:
- Albert W. Girotti and Witold Korytowski
- Book:
- Singlet Oxygen: Applications in Biosciences and Nanosciences (year: 2015, volume: x, pages: xxx), Publisher: Royal Society of Chemistry Publisher, England
- Status:
- Accepted for publication