Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Pharmacogenetics in predicting metabolic ratio of tamoxifen; genome-wide association study linked to mass spectrometry-based analyses

2011/01/B/NZ2/05374

Keywords:

tamoxifen breast cancer polymorphism association studies mass spectrometry

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_3: Proteomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Hennig 

Number of co-investigators in the project: 12

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 648 000 PLN

Project start date (Y-m-d): 2011-12-12

Project end date (Y-m-d): 2014-12-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Common low-penetrance risk variants associated with breast cancer in Polish women
    Authors:
    Ledwoń JK, Hennig EE*, Maryan N, Goryca K, Nowakowska D, Niwińska A, Ostrowski J
    Academic press:
    BMC Cancer (rok: 2013, tom: 0,895833333333333, strony: 45300), Wydawca: BioMedCentral
    Status:
    Published
    DOI:
    10.1186/1471-2407-13-510 - link to the publication
  2. Limited predictive value of achieving beneficial plasma (Z)-endoxifen threshold level by CYP2D6 genotyping in tamoxifen-treated Polish women with breast cancer
    Authors:
    Hennig EE*, Piatkowska M, Karczmarski J, Goryca K, Brewczynska E, Jazwiec R, Kluska A, Omiotek R, Paziewska A, Dadlez M, Ostrowski J.
    Academic press:
    BMC Cancer (rok: 2015, tom: 1,02083333333333, strony: 45303), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12885-015-1575-4 - link to the publication