Single-chained ether lipids in 2D model lipid membranes - the attempt to explain the differences in the membrane activity of these compounds

2011/01/B/ST4/00910

Keywords

Descriptors

  • ST4_5: Chemia i fizykochemia powierzchni

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Jagielloński, Wydział Chemii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Hąc-Wydro

Number of co-investigators in the project: 3

Call

OPUS 1 – announced on 2011-03-15

Amount awarded
262 600 PLN
Project start date
2011-12-01
Project end date
2013-11-30
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Termostat z chłodzeniem. Cost: 20 000 PLN
  2. Waga analityczna. Cost: 32 000 PLN
  3. notebook.
  4. urządzenie wielofunkcyjne (drukarka, skaner, kopiarka).

Information in the final report

Publication in academic press/journals (6)

  1. Behavior of platelet activating factor in membrane-mimicking environment. Langmuir monolayer study complemented with grazing incidence X-ray diffraction and Brewster angle microscopy

    Authors:
    Michał Flasiński, Marcin Broniatowski, Paweł Wydro, Katarzyna Hąc-Wydro, Patrycja DynarowiczŁątka
    Academic press:
    The Journal of Physical Chemistry B (year: 2012, volume: 116, pages: 10842-10855), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/jp302907e – link to the publication
  2. Towards the understanding of the behavior of single-chained ether phospholipids in model biomembranes: Interactions with phosphatidylethanolamines in Langmuir monolayers

    Authors:
    Katarzyna Hąc-Wydro, Michał Flasiński, Paweł Wydro, Patrycja Dynarowicz-Łątka
    Academic press:
    Colloids and Surfaces B: Biointerfaces (year: 2012, volume: 97, pages: 162-170), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2012.04.023 – link to the publication
  3. Comparative characteristics of membrane-active single-chained ether phospholipids: PAF and Lyso-PAF in Langmuir monolayers

    Authors:
    Michał Flasiński, Marcin Broniatowski, Paweł Wydro, Patrycja Dynarowicz-Łątka
    Academic press:
    The Journal of Physical Chemistry B (year: 2012, volume: 116, pages: 3155-3163), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/jp2121092 – link to the publication
  4. Interactions between single-chained ether phospholipids andsphingomyelin in mixed monolayers at the air/waterinterface—Grazing incidence X-ray diffraction and Brewster anglemicroscopy studies

    Authors:
    Michał Flasiński, Katarzyna Hąc-Wydro, Paweł Wydro, Marcin Broniatowski, Patrycja Dynarowicz-Łątka
    Academic press:
    Colloids and Surfaces B: Biointerfaces (year: 2013, volume: 111, pages: 43-51), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2013.05.024 – link to the publication
  5. Cholesterol as a factor regulating the influence of natural (PAF and lysoPAF) vs synthetic (ED) ether lipids on model lipid membranes

    Authors:
    Michał Flasiński, Paweł Wydro, Katarzyna Hąc-Wydro, Patrycja Dynarowicz-Łątka
    Academic press:
    Biochimica et Biophysica Acta (year: 2013, volume: 1828, pages: 2700-2708), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2013.07.024 – link to the publication
  6. Influence of PAF, lyso-PAF and edelfosine on model Langmuir monolayers imitating plasma membranes of cell lines differing in susceptibility to anticancer treatment. The effect of plasmalogen level.

    Authors:
    Michał Flasiński, Katarzyna Hąc-Wydro, Paweł Wydro, Patrycja Dynarowicz-Łątka
    Status:
    Accepted for publication

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Graphic design and implementation: Jakub Piotrowski