Normal021falsefalsefalseMicrosoftInternetExplorer4/* Style Definitions */table.MsoNormalTable{mso-style-name:Standardowy;mso-tstyle-rowband-size:0;mso-tstyle-colband-size:0;mso-style-noshow:yes;mso-style-parent:"";mso-padding-alt:0cm 5.4pt 0cm 5.4pt;mso-para-margin:0cm;mso-para-margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:10.0pt;font-family:"Times New Roman";mso-ansi-language:#0400;mso-fareast-language:#0400;mso-bidi-language:#0400;}DNA damage-induced signalling pathways leading to senescence of cancer cells
2011/01/M/NZ1/01597
Keywords
Descriptors
- NZ1_1: Biologia molekularna
- NZ1_7: Inżynieria komórkowa
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 7
Call
HARMONIA 1 – announced on 2011-03-15
- Amount awarded
- 724 000 PLN
- Project start date
- 2011-12-06
- Project end date
- 2014-12-05
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Mikroskop odwrócony MBI100T firmy Mikrolab z kontrastem fazowym.
- Przestrajany ciekłokrystaliczny filtr RGB do kamery Retiga 1300.
- wirówka z chłodzeniem. Cost: 24 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes
- Authors:
- Olga Alster, Anna Bielak-Zmijewska, Grazyna Mosieniak, Maria Moreno-Villanueva, Wioleta Dudka- Ruszkowska, Aleksandra Wojtala, Monika Kusio-Kobiałka, Zbigniew Korwek, Alexander Burkle, Katarzyna Piwocka, Jan K. Siwicki, Ewa Sikora
- Academic press:
- PlosOne (year: 2014, volume: 9, pages: e104964), Publisher: Public Library of Science
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0104964. – link to the publication
-
Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favour Escape From Senescence
- Authors:
- Mosieniak G, Sliwinska MA, Alster O, Strzeszewska A, Sunderland P, Piechota M, Was H, Sikora E
- Academic press:
- Neoplasia (year: 2015, volume: 17, pages: 882-893), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neo.2015.11.008 – link to the publication
-
Curcumin induces permanent growth arrest of human colon cancer cells: Link between senescence and autophagy
- Authors:
- Mosieniak G, Adamowicz M, Alster O, Jaskowiak H, Szczepankiewicz AA, Wilczynski GM, Ciechomska IA, Sikora E.
- Academic press:
- Mechanism of Aging and Development (year: 2012, volume: 133(6), pages: 444-455), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.mad.2012.05.004 – link to the publication
-
Morphological and functional characteristic of senescent cancer cells
- Authors:
- Ewa Sikora, Grażyna Mosieniak, Malgorzata Alicja Sliwinska
- Academic press:
- Current Drugs Targets (year: 2016, volume: 17, pages: 377-387), Publisher: Bentham Science
- Status:
- Published