Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular classification of medulloblastoma based on transcriptional signature: prognostic and therapeutic implications

2011/01/B/NZ4/01066

Keywords:

Medulloblastoma genes expression clinical correlations

Descriptors:

  • NZ4_11: Metabolism
  • NZ4_5: Anatomical pathology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

INSTYTUT - POMNIK CENTRUM ZDROWIA DZIECKA

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maria Łastowska 

Number of co-investigators in the project: 9

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 453 300 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2015-06-15

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termocykler gradientowy na 48 próbek 0,2 ml (22 000 PLN)
  2. Program komputerowy do analizy wyników mikromacierzy (GeneSpring) (52 600 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. Contrast enhancement pattern predicts poor survival for patients with non-WNT/SHH medulloblastoma tumours
    Authors:
    Maria Łastowska, Elżbieta Jurkiewicz, Joanna Trubicka, Paweł Daszkiewicz, Monika Drogosiewicz, Katarzyna Malczyk , Wiesława Grajkowska , Ewa Matyja , Bożena Cukrowska, Maciej Pronicki , Marta Perek-Polnik, Danuta Perek, Bożenna Dembowska-Bagińska
    Academic press:
    Journal of Neuro-Oncology (rok: 2015, tom: 23, strony: 65–73), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11060-015-1779-0 - link to the publication
  2. Identification of a novel inherited ALK variant M1199L in the WNT type of medulloblastoma
    Authors:
    Joanna Trubicka, Małgorzata Szperl, Wiesława Grajkowska, Agnieszka Karkucińska Więckowska, Magdalena Tarasińska, Katarzyna Falana, Marta Perek-Polnik, Bożenna Dembowska-Bagińska, Maria Łastowska
    Academic press:
    Folia Neuropathologica (rok: 2016, tom: 54 (1), strony: 23-30), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/fn.2016.58912 - link to the publication
  3. The germline variants in genes encoding BRCA1-associated genome surveillance complex (BASC) subunits in pediatric medulloblastoma: a new challenge for current therapeutic strategies
    Authors:
    Joanna Trubicka, Tomasz Żemojtel, Jochen Hecht3, Katarzyna Falana1, Dorota Piekutowska- Abramczuk, Marta Perek-Polnik, Monika Drogosiewicz, Wiesława Grajkowska, Elżbieta Ciara, Elżbieta Moszczyńska, Bożenna Dembowska-Bagińska, Krystyna H. Chrzanowska, Małgorzata Krajewska-Walasek, Maria Łastowska
    Academic press:
    BMC Cancer (rok: 2016, ), Wydawca: Springer
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. PROGNOSTIC VALUE OF TP53 MUTATIONS IN SHH TYPE OF PEDIATRIC MEDULLOBLASTOMA
    Authors:
    Joanna Trubicka, Maria Borucka-Mankiewicz, Elzbieta Ciara,Krystyna Chrzanowska, Marta Perek-Polnik, Dorota Abramczuk-Piekutowska, Wieslawa Grajkowska, Dorota Jurkiewicz, Sylwia Luczak, Pawel Kowalski, Malgorzata Krajewska-Walasek, Maria Łastowska
    Conference:
    16th International Symposium on Pediatric Neuro-Oncology (ISPNO), Singapore (rok: 2014, ), Wydawca: OXFORD UNIV PRESS INC, JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
    Data:
    konferencja -JUN 28JUL 02, 2014
    Status:
    Published
    DOI:
    link to the publication
  2. RETICULIN-POSITIVE DESMOPLASTIC/NODULAR TUMOURS ARE ASSOCIATED EXCLUSIVELY WITH SHH GROUP OF MEDULLOBLASTOMA
    Authors:
    Wieslawa Grajkowska, Maciej Pronicki, Bozena Cukrowska,Bozenna Dembowska-Baginska, and Maria Łastowska;
    Conference:
    16th International Symposium on Pediatric Neuro-Oncology (ISPNO), Singapore (rok: 2014, ), Wydawca: OXFORD UNIV PRESS INC, JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
    Data:
    konferencja JUN 28-JUL 02, 2014
    Status:
    Published
    DOI:
    link to the publication
  3. Transcriptional profiles of medulloblastoma tumours correlate with the location of tumour
    Authors:
    Maria Łastowska, Elżbieta Jurkiewicz, Paweł Daszkiewicz, Monika Drogosiewicz, Joanna Trubicka, Wiesława Grajkowska, Maciej Pronicki
    Conference:
    16th International Symposium on Pediatric Neuro-Oncology (ISPNO), Singapore (rok: 2014, ), Wydawca: OXFORD UNIV PRESS INC, JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA
    Data:
    konferencja JUN 28-JUL 02, 2014
    Status:
    Published
  4. Transcriptional profiles of medulloblastoma tumours: Correlation with clinical and histopathological features. An experience from a single institution.
    Authors:
    Maria Łastowska, Marta Perek-Polnik, Wiesława Grajkowska, Katarzyna Malczyk, Bożena Cukrowska, Bożenna Dembowska-Bagińska, Danuta Perek.
    Conference:
    44th Congress of the International Society of Paediatric Oncology (SIOP), London (rok: 2012, ), Wydawca: WILEY PERIODICALS, INC, ONE MONTGOMERY ST, SUITE 1200, SAN FRANCISCO, CA 94104 USA
    Data:
    konferencja 5-8.10.2012
    Status:
    Published

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