Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Small non-coding microRNAs in differentiation of autoreactive lymphocites T helpers - significance in patogenesis of autoimmune demyelination.

2011/01/N/NZ6/01849

Keywords:

MicroRNA multiple sclerosis autoimmunology lymphocytes T helper

Descriptors:

  • NZ6_3: Animal immunology
  • NZ6_1: Adaptive and innate immunity
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maria Cichalewska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 195 000 PLN

Project start date (Y-m-d): 2011-12-13

Project end date (Y-m-d): 2014-12-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do elektroforezy Bioanalyzer Agilent (55 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  • Book publications / chapters in book publications (1)
  1. Brain glycolipids suppress T helper cells inhibit autoimmune demyelination.
    Authors:
    Mycko MP, Sliwinska B, Cichalewska M, Cwiklinska H, Raine CS, Selmaj KW
    Academic press:
    Journal of Neuroscience (rok: 2014, tom: 34(25), strony: 8646-58), Wydawca: Journal of Neuroscience
    Status:
    Published
    DOI:
    10.1523/JNEUROSCI.0885-14.2014 - link to the publication
  2. MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination.
    Authors:
    Mycko MP, Cichalewska M, Machlanska A, Cwiklinska H, Mariasiewicz M, Selmaj KW.
    Academic press:
    Proceedings of the National Academy of Sciences (rok: 2012, tom: 109(20), strony: 1248-57), Wydawca: National Academy of Science
    Status:
    Published
    DOI:
    10.1073/pnas.1114325109 - link to the publication
  3. Plasmocytoid dendritic cell deficit of early response to toll-like receptor 7 agonist stimulation in multiple sclerosis patients.
    Authors:
    Mycko MP, Cwiklinska H, Cichalewska M, Matysiak M, Lewkowicz P, Sliwinska B, Selmaj I, Selmaj KW
    Academic press:
    Clinical Immunology (rok: 2014, tom: 153(1):211-9, strony: 153(1):211-9), Wydawca: Clinical Immunology Society
    Status:
    Published
    DOI:
    10.1016/j.clim.2014.04.016 - link to the publication
  4. Dysregulated RNA-induced silencing complex (RISC) assembly within CNS corresponds with miRNA abnormal expression during autoimmune demyelination
    Authors:
    Krzysztof Selmaj, Przemyslaw Lewkowicz, Hanna Cwiklinska, Marcin Mycko, Maria Cichalewska, Malgorzata Domowicz, Natalia Lewkowicz, Anna Jurewicz
    Academic press:
    The Journal of Neuroscience , Wydawca: Society for Neuroscience
    Status:
    Submitted
    DOI:
    brak - link to the publication
  1. MicroRNA control of an experimental autoimmune encephalomyelitis
    Authors:
    Mycko, M.; Cichalewska, M.; Cwiklinska, H.; et al.
    Conference:
    ECTRIMS 2013 (rok: 2013, ), Wydawca: MULTIPLE SCLEROSIS JOURNAL Volume: 19 Issue: 11
    Data:
    konferencja 2-5 october
    Status:
    Published
  2. Mir-301a Regulation of the Development of a Th17 Response Controls Autoimmune Demyelination
    Authors:
    Mycko, M; Cichalewska, M; Machlanska, A; Cwiklinska, H; Mariasiewicz, M; Selmaj, K
    Conference:
    64th Annual Meeting of the American-Academy-of-Neurology (AAN) (rok: 2012, ), Wydawca: LIPPINCOTT WILLIAMS & WILKINS
    Data:
    konferencja APR 21-28
    Status:
    Published
  3. MicroRNA-155 regulates T helper cell autoimmunity during autoimmune demyelination via Hsp40 genes expression.
    Authors:
    M. Cichalewska, M. Mycko, H. Cwiklinska, B. Sliwinska, K. Selmaj.
    Conference:
    ECTRIMS 2013 (rok: 2013, ), Wydawca: MULTIPLE SCLEROSIS JOURNAL Volume: 19 Issue: 11
    Data:
    konferencja 2-5 october
    Status:
    Published
  4. miR-155 REGULATION OF AUTOIMMUNE DEMYELINATION VIA HEAT SHOCK PROTEIN 40 FAMILY GENES EXPRESSION
    Authors:
    Maria B Cichalewska, Marcin P Mycko, Hanna Cwiklinska, Maciej Jurynczyk, Krzysztof W Selmaj
    Conference:
    Regulatory&Non-Coding RNAs (rok: 2014, ), Wydawca: Cold Spring Harbor Laboratory Meetings and Courses
    Data:
    konferencja 21-26 08 2014
    Status:
    Published
  5. MicroRNA as a therapeutic target in Multiple Sclerosis
    Authors:
    Mycko, Marcin; Cichalewska, Maria; Ćwiklińska Hanna; Śliwińska Beata; Krzysztof Selmaj.
    Conference:
    American Academy of Neurology, 65th AAN Annual Meeting (rok: 2013, ), Wydawca: Lippocott Williams&Wilkins
    Data:
    konferencja 16-23 March
    Status:
    Published
  6. microRNA-301a regulates myelin-autoreactive T helper type 17 cell differentation
    Authors:
    Marcin P. Mycko, Maria Cichalewska, Agnieszka Machlanska, Magdalena Mariasiewicz, Hanna Cwiklinska, Krzysztof W. Selmaj
    Conference:
    IL-17 and related cytokines (rok: 2012, ), Wydawca: Biomedical Press
    Data:
    konferencja 18-21 06
    Status:
    Published
  1. Małe niekodujące RNA w stwardnieniu rozsianym
    Authors:
    Marcin Mycko, Maria Cichalewska, Krzysztof Selmaj
    Book:
    Stwardnienie Rozsiane (rok: 2013, tom: 9788363622992, strony: 45620), Wydawca: Termedia
    Status:
    Published

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