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Information on the principal investigator and host institution

Information of the project and the call

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Novel angiotensin peptides - formation and role in adipose tissue in rat model of obesity and insulin resistance

2011/01/M/NZ4/03752

Keywords:

angiotensin adipose tissue obesity diabetes

Descriptors:

  • NZ4_6: Endocrinology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Rafał Olszanecki 

Number of co-investigators in the project: 5

Call: HARMONIA 1 - announced on 2011-03-15

Amount awarded: 260 000 PLN

Project start date (Y-m-d): 2011-12-19

Project end date (Y-m-d): 2014-08-18

Project duration:: 32 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (6)
  1. The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice.
    Authors:
    Olszanecki R, Suski M, Gebska A, Toton-Zuranska J, Kus K, Madej J,Bujak-Gizycka B, Jawien J, Korbut R
    Academic press:
    J Physiol Pharmacol. (rok: 2013, tom: Jun;64(3), strony: 317-20.), Wydawca: Polskie Towarzystwo Fizjologiczne
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Differential regulation of oxytocin receptor in various adipose tissue depots and skeletal muscle types in obese Zucker rats
    Authors:
    L. Gajdosechova, K. Krskova, R. Olszanecki, S. Zorad
    Academic press:
    Hormone and Metabolic Research (rok: 2015, tom: 47(08): 600-604, strony: 600-604), Wydawca: Georg Thieme Verlag
    Status:
    Published
    DOI:
    10.1055/s-0034-1395677 - link to the publication
  3. Hypooxutocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue
    Authors:
    Gajdosechova L, Krskova K, Belen-Segarra A, Spolcova A, Suski M, Olszanecki R, Zorad S.
    Academic press:
    Journal of Endocrinology (rok: 2014, tom: 220, strony: 333-343), Wydawca: Society of Endocrinology, UK
    Status:
    Published
    DOI:
    10.1530/JOE-13-0417 - link to the publication
  4. Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats
    Authors:
    Spolcova A, Mikula B, Krskova K, Gajdosechova L, Zorad S, Olszanecki R, Suski M, Bujak-Giżycka B, Zelezna B, Maletinska L.
    Academic press:
    BMC Neuroscience (rok: 2014, tom: 0,702083333333333, strony: ---), Wydawca: BioMed Central Ltd. Part of Springer Science+Business Media
    Status:
    Published
    DOI:
    10.1186/1471-2202-15-111 - link to the publication
  5. Influence of atorvastatin on angiotensin I metabolism in resting and TNF-α-activated rat vascular smooth muscle cells
    Authors:
    Suski M, Gebska A, Olszanecki R, Stachowicz A, Uracz D, Madej J, Korbut R
    Academic press:
    J Renin Angiotensin Aldosterone Syst. (rok: 2013, tom: Feb 6 (Epub ), strony: 45297), Wydawca: http://www.sagepublications.com
    Status:
    Published
    DOI:
    10.1177/1470320313475907 - link to the publication
  1. Elevated adipose and liver IRAP/oxytocinase activity may account for increased oxytocin degradation in obesity. Effect of IRAP blockade on obese phenotype
    Authors:
    L. Gajdosechova, K. Krskova, M. Suski, S.Y. Chai, R. Olszanecki, S. Zorad
    Conference:
    Joint meeting of the Federation of European Physiological Societies (FEPS) and the Hungarian Physiological Society, (rok: 2014, ), Wydawca: Acta Physiologica Volume 211, Issue Supplement s697; Scandinavian Physiological Society. Published by John Wiley & Sons Ltd
    Data:
    konferencja 27-30 August 2014, Budapest, Hungary
    Status:
    Published
  2. Chronic treatment of rats with oxytocin upregulates renin and (pro)renin receptor expression in kidney
    Authors:
    K. Krskova, L. Gajdosechova, S. Zorad, D. Jezova, R. Olszanecki
    Conference:
    Joint meeting of the Federation of European Physiological Societies (FEPS) and the Hungarian Physiological Society (rok: 2014, ), Wydawca: Acta Physiologica, Volume 211, Issue Supplement s697; Scandinavian Physiological Society. Published by John Wiley & Sons Ltd
    Data:
    konferencja 27-30 August 2014, Budapest, Hungary
    Status:
    Published
  3. Ex vivo assessment of tissue angiotensin metabolism. Focus on Ang I/Ang IV/IRAP axis in various kinds of fat tissue in rat model of obesity and insulin resistance
    Authors:
    R. Olszanecki, B. Bujak-Giżycka, M. Suski, L. Gajdosechova, K. Krskova, S. Zorad, R. Korbut
    Conference:
    Joint meeting of the Federation of European Physiological Societies (FEPS) and the Hungarian Physiological Society (rok: 2014, ), Wydawca: Acta Physiologica Volume 211, Issue Supplement s697; Scandinavian Physiological Society. Published by John Wiley & Sons Ltd
    Data:
    konferencja 27-30 August 2014, Budapest, Hungary
    Status:
    Published
  4. Influence of atorvastatin on angiotensin I metabolism in rat vascular smooth muscle cells
    Authors:
    2.Gębska A., Suski M., Olszanecki R., Stachowicz A., Lorkowska-Zawicka B., Uracz D., Madej J., Korbut R
    Conference:
    XVIIIth International Congress of the Polish Pharmacological Society, Kazimierz Dolny (rok: 2013, ), Wydawca: Pharmacological Reports, Elsevier
    Data:
    konferencja 23-25 May 2013
    Status:
    Published
  5. Angiotensin I metabolism in various kinds of fat tissue - ex vivo study in rat model of obesity and insulin resistance
    Authors:
    Bujak-Gizycka B, Suski M, Madej J, Bystrowska B, Zorad S, Gajdosechova L, Krskova K, Olszanecki R, Korbut R.
    Conference:
    32nd European Peptide Symposium, (rok: 2012, ), Wydawca: Journal of Peptide Science, Wiley-Blackwell,DOI: 10.1002/psc.2449
    Data:
    konferencja 2-7 September 2012
    Status:
    Published
  6. Metabolism of angiotensin-(1-12) in adipose tissue – ex vivo study in rat model of hypertension.
    Authors:
    Bujak-Giżycka B., Madej J., Suski M., Kuś K., Zorad S., Olszanecki R., Korbut R
    Conference:
    XVIIIth International Congress of the Polish Pharmacological Society, Kazimierz Dolny (rok: 2013, ), Wydawca: Pharmacological Reports, Elsevier
    Data:
    konferencja 23-25 May 2013
    Status:
    Published

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