Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Search for the mechanism inactivating TP53 function in neoplastic cells showing single heterozygous mutations of this gene

2011/01/B/NZ1/01502

Keywords:

TP53 WRAP53 PIN3 TP53 isoforms miRNA 125

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ4_11: Metabolism

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Rieske 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 382 500 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2014-12-05

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termocykler do reakcji PCR (15 000 PLN)
  2. Zasilacz i aparat do elektroforezy agarozowej (4 389 PLN)
  3. Zestaw pipet automatycznych (4 168 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. PIN3 duplication may be partially responsible for TP53 haploinsufficiency
    Authors:
    Winiecka-Klimek M1, Szybka M, Rieske P, Piaskowski S, Bienkowski M, Walczak M, Pacholczyk M, Rostkowski M, Zieba J, Banaszczyk M, Hulas-Bigoszewska K, Peciak J, Pawliczak R, Stoczynska-Fidelus E.
    Academic press:
    BMC Cancer (rok: 2014, tom: 1,04791666666667, strony: brak), Wydawca: BMC
    Status:
    Published
    DOI:
    10.1186/1471-2407-14-669 - link to the publication
  2. Genetic heterogeneity of a T-acute lymphoblastic leukemia cell line, RPMI-8402
    Authors:
    Ewelina Stoczynska-Fidelus , Sylwester Piaskowski, Roza Pawlowska , Malgorzata Szybka , Joanna Peciak, Krystyna Hulas-Bigoszewska, Marta Winiecka-Klimek, Piotr Rieske
    Academic press:
    Onclology Letters (rok: 2015, tom: 11(1), strony: 593-599), Wydawca: Spandidos, Mimet House, 5a Praed Street, London W2 1NJ, United Kingdom
    Status:
    Published
    DOI:
    10.3892/ol.2015.3959 - link to the publication
  3. Spontaneous in vitro senescence of glioma cells confirmed by an antibody against IDH1R132H
    Authors:
    Stoczynska-Fidelus E, Och W, Rieske P, Bienkowski M, Banaszczyk M, Winiecka-Klimek M, Zieba J, Janik K, Rosiak K, Treda C, Stawski R, Radomiak-Zaluska A, Piaskowski S
    Academic press:
    Anticancer Research (rok: 2014, tom: 34(6), strony: 2859-67), Wydawca: International Institue of Anticancer Research
    Status:
    Published
    DOI:
    brak - link to the publication
  1. POTENTIAL MECHANISM RESPONSIBLE FOR HIGHER EXPRESSION OF TP53 MUTATED ALLELE
    Authors:
    Marta Winiecka, Ewelina Stoczynska-Fidelus, Małgorzata Szybka,Michal Bienkowski, Maciej Walczak, Sylwester Piaskowski, Mateusz Banaszczyk, Krystyna Hulas-Bigoszewska, Piotr Rieske
    Conference:
    5th international conference od drug discovery and therapy (rok: 2013, ), Wydawca: Dubai Womens College
    Data:
    konferencja 18-21 luty 2013
    Status:
    Published

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