Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Synthesis and application of multi-task, selective drug carriers to reduce the cardiotoxity and photosensitivity of anthracyclin antibiotics.

2011/01/N/ST5/05550

Keywords:

doxorubicin cyclodextrin nitroxyl radical TEMPO drug delivery systems cardiotoxity.

Descriptors:

  • ST5_3: Surface modification
  • ST5_12: Methods of nanomaterials/materials synthesis
  • ST5_22:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Olga Święch 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 225 900 PLN

Project start date (Y-m-d): 2011-12-19

Project end date (Y-m-d): 2014-10-18

Project duration:: 34 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. ML54/M01 Waga analityczna (9 200 PLN)
  2. Komputer z procesorem 16-rdzeniowym (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. pH - sensitive monosubstituted β-cyclodextrins
    Authors:
    Kamila Żelechowska, Olga Święch, Renata Bilewicz.
    Academic press:
    Molecules (rok: 2014, ), Wydawca: MDPI Open Access Journals Platform
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Cyclodextrin Derivatives Conjugated with Aromatic Moieties as pHresponsive Drug Carriers for Anthracycline
    Authors:
    Olga Święch, Paula Dutkiewicz, Karolina Wójciuk, Kazimierz Chmurski, Marcin Kruszewski, Renata Bilewicz
    Academic press:
    The Journal of Physical Chemistry B (rok: 2013, tom: 117, strony: 13444 – 13450), Wydawca: ACS Publication
    Status:
    Published
    DOI:
    10.1021/jp4060632 - link to the publication
  3. NIR – sensitive anisotropic Au2S/Au nanoparticles conjugated with doxorubicin.
    Authors:
    Olga Swiech, Lidia Jagoda Opuchlik, Karolina Wojciuk, Marcin Kruszewski, Renata Bilewcz
    Academic press:
    Journal of Materials Chemistry B (rok: 2015, tom: bd, strony: bd), Wydawca: Royal Society of Chemistry
    Status:
    Submitted
    DOI:
    brak - link to the publication

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