Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Glutaminergic system and brain tolerance to ischemia – role of transporting systems (EAAT2 and xc-)

2011/01/B/NZ4/00783

Keywords:

focal ischemia brain preconditioning Glu transporters microdialysis expression

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Pera 

Number of co-investigators in the project: 6

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 467 100 PLN

Project start date (Y-m-d): 2011-12-15

Project end date (Y-m-d): 2014-12-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. mikroskop fluorescencyjny wraz z systemem obróbki danych (70 000 PLN)
  2. pompy infuzyjne (2 szt.) (23 564 PLN)
  3. zestaw do laserowego dopplerowskiego monitorowania przepływu krwi.

Information in the final report

  • Publication in academic press/journals (3)
  1. GLUTAMATE TRANSPORTERS IN BRAIN ISCHEMIA: TO MODULATE OR NOT?
    Authors:
    Krzyżanowska W, Pomierny B, Filip M, Pera J
    Academic press:
    Acta Pharmacologica Sinica (rok: 2014, tom: 35, strony: 444-62), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/aps.2014.1 - link to the publication
  2. Ceftriaxone and N-acetylcysteine as preconditioning strategies in focal brain ischemia: influence on glutamate transporters expression
    Authors:
    Krzyżanowska W, Pomierny B, Filip M, Pera J
    Academic press:
    Neurotoxicity Research (rok: 2016, tom: 29, strony: 539-50), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-016-9602-z - link to the publication
  3. Ceftriaxone- and N-acetylcysteine-induced brain tolerance to ischemia: Influence on glutamate levels in focal cerebral ischemia
    Authors:
    Krzyżanowska W, Pomierny B, Bystrowska B, Pomierny-Chamioło L, Filip M, Budziszewska B, Pera J
    Academic press:
    PLoS One (rok: 2017, tom: 12, strony: e0186243), Wydawca: San Francisco, CA : Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0186243 - link to the publication

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