Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Interaction of dopamine receptors with G proteins – structural and kinetic aspects

2011/01/B/NZ1/00114

Keywords:

dopamine receptors D1 and D2 G proteins antipsychotic drugs FRET BiFC

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Polit 

Number of co-investigators in the project: 6

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 387 000 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Bomba do niszczenia komórek (10 000 PLN)
  2. Ekstruder liposomowy (8 000 PLN)
  3. Sonikator ultradźwiękowy (20 950 PLN)
  4. Komputer wraz z oprogramowaniem (5 200 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Comparative EPR studies on lipid bilayer properties in nanodiscs and liposomes
    Authors:
    Stepien P., Polit A., Wisniewska-Becker A.
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Biomembranes (rok: 2015, tom: 1848, strony: 60-66), Wydawca: Elsevier
    Status:
    Published
  2. New insights into the model of dopamine D1 receptor and G-proteins interactions
    Authors:
    Mystek P., Tworzydło M., Dziedzicka-Wasylewska M. i Polit A.
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2015, tom: 1853, strony: 594–603), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2014.12.015 - link to the publication