Projects funded by the NCN
Development of cellular models for the investigation of histamine H3 and H4 receptors pharmacology.
2011/01/N/NZ4/01126
Keywords:
histamine H3 and H4 receptors radioligand binding tests functional assays stable expression of recombinant proteins
Descriptors:
- NZ4_16:
- NZ4_17:
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Uniwersytet Jagielloński, Uniwersytet Jagielloński - Collegium Medicum, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 1 - announced on 2011-03-15
Amount awarded: 115 300 PLN
Project start date (Y-m-d): 2011-12-16
Project end date (Y-m-d): 2014-12-15
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Automatyczny system do zasysania cieczy, wyposażony w pojemnik na odpady i filtr wyjaławiający. (6 000 PLN)
- Homogenizator Ultra-Turrax (4 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Development of novel cellular model for affinity studies of histamine H4 receptor ligands.Authors:Tadeusz Karcz, Katarzyna Kieć-KononowiczAcademic press:Acta Biochimica Polonica (rok: 2013, tom: 60(4), strony: 823-827), Wydawca: Polish Biochemical Society and of the Committee of Biochemistry and Biophysics Polish Academy of SciencesStatus:PublishedDOI:PMID: - link to the publication
- (2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligandsAuthors:Katarzyna Kamińska, Julia Ziemba, Joanna Ner, Johannes Stephan Schwed, Dorota Łażewska, Małgorzata Więcek, Tadeusz Karcz, Agnieszka Olejarz, Gniewomir Latacz, Kamil Kuder, Tim Kottke, Małgorzata Zygmunt, Jacek Sapa, Janina Karolak-Wojciechowska, Holger Stark, Katarzyna Kieć-KononowiczAcademic press:European Journal of Medicinal Chemistry (rok: 2015, tom: 103, strony: 238-251), Wydawca: Editions Scientifiques Elsevier, Paryż, FrancjaStatus:PublishedDOI:10.1016/j.ejmech.2015.08.014 - link to the publication