Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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HAX-1 role in regulation of cell motility and invasive potential

2011/01/B/NZ1/03674

Keywords:

HAX-1 cell motility Arp2/3 complex HAX-1 interactome

Descriptors:

  • NZ2_3: Proteomics
  • NZ2_7: Bioinformatics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Grzybowska 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 380 000 PLN

Project start date (Y-m-d): 2011-12-19

Project end date (Y-m-d): 2015-12-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termomikser Eppendorf (9 838 PLN)
  2. Automatyczny licznik komórek TC 10 (BioRad) (12 000 PLN)
  3. Pipeta Eppendorf Xlprorer (5 000 PLN)
  4. Pipety Gilson (7 961 PLN)
  5. Komora PCR model UVC/T-AR (Biogenet) (5 000 PLN)
  6. Wirówka laboratoryjna MPW 251 (28 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. HAX-1: a novel P-body protein
    Authors:
    Zayat V, Balcerak A, Korczynski J, Trebinska A, Wysocki J, Sarnowska E, Chmielarczyk M, Macech E, Konopiński R, Dziembowska M, Grzybowska EA
    Academic press:
    DNA and Cell Biology (rok: 2015, tom: 34(1), strony: 43-54), Wydawca: Mary Ann Liebert, Inc.
    Status:
    Published
    DOI:
    10.1089/dna.2014.2657 - link to the publication
  2. Migracja i inwazyjność komórek nowotworowych; rola plastyczności komórek i udział macierzy zewnątrzkomórkowej w tworzeniu przerzutów.
    Authors:
    Balcerak A, Wakuła M, Trębińska A, Grzybowska EA.
    Academic press:
    Nowotwory (rok: 2016, tom: 66 (1), strony: 45-52), Wydawca: VM Media
    Status:
    Published
  3. Exploring the anti-apoptotic role of HAX-1 versus BCL-X-L in cytokine-dependent bone marrow-derived cells from mice
    Authors:
    Trebinska, A; Hoegstrand, K; Grandien, A; Grzybowska, EA; Fadeel, B
    Academic press:
    FEBS Letters (rok: 2014, tom: 588, strony: 2921-2927), Wydawca: ELSEVIER SCIENCE BV
    Status:
    Published
    DOI:
    10.1016/j.febslet.2014.05.042 - link to the publication
  4. The calcium binding properties and structure prediction of the Hax-1 protein
    Authors:
    Anna Balcerak, Sebastian Rowinski, Lukasz M. Szafron, Ewa A. Grzybowska
    Academic press:
    Acta Biochimica Polonica (rok: 2017, tom: 64(3), strony: 537-542), Wydawca: The Journal of the Polish Biochemical Society and of the Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.18388/abp.2017_1529 - link to the publication
  5. HAX1 role in promoting breast cancer metastasis can be linked to its impact on collective migration, adhesion and contractility.
    Authors:
    Alicja Trebinska-Stryjewska, Anna Balcerak, Maciej Wakula, Lukasz Szafron, Alina Rembiszewska, Mateusz Chmielarczyk, Urszula Smietanka, Renata Sienkiewicz-Kozlowska, Joanna Owczarek, Anna Felisiak-Golabek, Tymon Rubel, Sylwia Tabor, Ewelina Macech-Klicka, Ryszard Konopinski, Ewa A. Grzybowska
    Academic press:
    Oncotarget (rok: 2018, tom: -, strony: -), Wydawca: Oncotarget
    Status:
    Submitted
  6. HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing.
    Authors:
    Grzybowska EA, Zayat V, Konopiński R, Trębińska A, Szwarc M, Sarnowska E, Macech E, Korczyński J, Knapp A, Siedlecki JA.
    Academic press:
    FEBS Journal (rok: 2013, tom: 11,6673611111111, strony: 256-272), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/febs.12066. - link to the publication
  1. HAX1 role in promoting breast cancer metastasis can be linked to its impact on collective migration, adhesion and contractility
    Authors:
    Alicja Trebinska-Stryjewska, Anna Balcerak, Maciej Wakula, Lukasz Szafron, Alina Rembiszewska, Mateusz Chmielarczyk, Urszula Smietanka, Renata Sienkiewicz-Kozlowska, Joanna Owczarek, Anna Felisiak-Golabek, Tymon Rubel, Sylwia Tabor, Ewelina Macech-Klicka, Ryszard Konopinski, Ewa A. Grzybowska
    Conference:
    XXIst Gliwice Scientific Meetings 2017 (rok: 2017, ), Wydawca: Association for the Support of Cancer Research, Maria Skłodowska-Curie Institute-Oncology Center, Gliwice Branch,Silesian University of Technilogy
    Data:
    konferencja 17-18 listopada 2017
    Status:
    Published