Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Riboflavin as an immunomodulator - the effect of the riboflavin deficiency and supplementation on the early stage of pathogen recognition and development of the immune response - in vitro and in vivo studies

2011/01/D/NZ6/02704

Keywords:

riboflavin macrophages mast cells inflammation ariboflavinosis LPS zymosan

Descriptors:

  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Wydział Nauk o Zdrowiu

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Mazur-Biały 

Number of co-investigators in the project: 6

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 365 000 PLN

Project start date (Y-m-d): 2011-12-12

Project end date (Y-m-d): 2014-12-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Boks termostatyczny przenośny do transportu próbek (1 000 PLN)
  2. Vortex (2 000 PLN)
  3. Zestaw pipet automatycznych (6 szt.) (6 000 PLN)
  4. Aparat fotograficzny z nakładką do mikroskopu (5 000 PLN)
  5. Laptop do obróbki i archiwizacji danych (3 000 PLN)
  6. Lodówka z zamrażalnikiem.
  7. Przenośna wirówka do osobistego użytku Mini Spin (Eppendorf) z rotorem (6 000 PLN)
  8. Zestaw do oceny zawartości tlenku azotu (7 500 PLN)
  9. Lodówka z zamrażalnikiem (3 000 PLN)
  10. Zestaw do automatycznej analizy liczby i żywotności komórek "Cell Counter" (14 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. HMGB1 inhibition during zymosan-induced peritonitis - the potential therapeutic action of riboflavin
    Authors:
    Agnieszka Irena Mazur-Bialy
    Academic press:
    American Journal of Physiology - Cell Physiology (rok: 2015, tom: -, strony: -), Wydawca: American Physiological Society
    Status:
    Submitted
  2. Riboflavin deprivation decrease macrophage viability and activity – study on RAW 264.7 cell line.
    Authors:
    Mazur-Bialy A.I., Buchala B., Plytycz B.
    Academic press:
    British Journal of Nutrition (rok: 2013, tom: 110, strony: 509-514), Wydawca: Cambridge University Press
    Status:
    Published
    DOI:
    10.1017/S0007114512005351 - link to the publication
  3. Immunomodulatory effect of riboflavin deficiency and enrichment - reversible pathological response versus silencing of inflammatory activation (a study on RAW 264.7 macrophages)
    Authors:
    Agnieszka Irena Mazur-Bialy, Ewa Pocheć, Barbara Plytycz
    Academic press:
    European Journal of Nutrition (rok: 2015, tom: -, strony: -), Wydawca: Springer
    Status:
    Submitted
  1. Riboflavin deficiency inhibits the viability and activity of macrophages RAW 264.7
    Authors:
    A. Mazur-Bialy, B. Plytycz
    Conference:
    Advances and Controversies in B-Vitamins and Choline (rok: 2012, ), Wydawca: Clin Chem Lab Med 2012;50(2):A1–A69
    Data:
    konferencja 5-8 marzec
    Status:
    Published