Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Personalized medicine for CLL

2011/01/B/NZ4/01702

Keywords:

chronic lymphocytic leukemia cellular signaling ex vivo induced apoptosis purine analogs cyclophosphamide/mafosfamide monoclonal antibody apoptosis-related proteins BCR Zap-70

Descriptors:

  • NZ4_11: Metabolism

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Rogalińska 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 435 380 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2013-12-15

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. wirówka (33 000 PLN)
  2. aparat do elektroforezy firmy BioRad (8 911 PLN)
  3. czytnik do chemiluminescencji (74 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Relationship between in vitro drug sensitivity and clinical response of patients to treatment in chronic lymphocytic leukemia
    Authors:
    Malgorzata Rogalinska, Jerzy Z. Błoński, Paweł Góralski, Ewa Wawrzyniak, Mariusz Hartman, Aneta Rogalska, Paweł Robak, Aneta Koceva-Chyła, Henryk Piekarski, Tadeusz Robak, Zofia M. Kiliańska
    Academic press:
    International Journal of Oncology (rok: 2015, tom: 46, strony: 1259-1267), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijo.2015.2823 - link to the publication
  2. The differences in thermal profiles between normal and leukemic cells exposed to anticancer drug evaluated by differential scanning calorimetry
    Authors:
    Paweł Góralski, Małgorzata Rogalińska, Jerzy Z. Błoński, Edyta Pytel,Tadeusz Robak, Zofia M. Kiliańska, Henryk Piekarski
    Academic press:
    Journal of Thermal Analysis and Calorimetry (rok: 2014, tom: 118, strony: 1339–1344), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10973-014-3957-2 - link to the publication
  3. Personalized therapy tests for the monitoring of chronic lymphocytic leukemia development
    Authors:
    Małgorzata Rogalińska, Paweł Góralski, Jerzy Z. Błoński, Paweł Robak, Jan Barciszewski, Aneta Koceva-Chyła, Henryk Piekarski, Tadeusz Robak, Zofia M. Kilianska
    Academic press:
    Oncology Letters , Wydawca: Spandidos Publications
    Status:
    Accepted for publication
    DOI:
    zaakceptowane - link to the publication
  4. Targeting Bcl-2 in CLL
    Authors:
    M. Rogalińska, ZM Kiliańska
    Academic press:
    Current Medicinal Chemistry (rok: 2012, tom: 19, strony: 5109-5115), Wydawca: Bentham
    Status:
    Published
    DOI:
    10.2174/092986712803530566 - link to the publication
  5. Toward personalized therapy for chronic lymphocytic leukemia: DSC and cDNA microarray assessment of two cases.
    Authors:
    Rogalińska M, Franiak-Pietryga I, Błoński JZ, Góralski P, Maciejewski H, Janus A, Robak P, Mirowski M, Piekarski H, Robak T, Kiliańska ZM
    Academic press:
    Cancer Biology & Therapy (rok: 2013, tom: 14, strony: 45455), Wydawca: Landes Bioscience
    Status:
    Published
    DOI:
    10.4161/cbt.22623. - link to the publication

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