Posttranscriptional control of putative cell cycle regulators SIAH1, SPINDLIN3 and TSC22D1 by PUMILIO2 protein in the human seminoma model

2011/01/B/NZ2/04833

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_5: Inżynieria genetyczna
  • NZ1_2: Biochemia

Panel

NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution

Instytut Genetyki Człowieka PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Barbara Ginter-Matuszewska

Number of co-investigators in the project: 6

Call

OPUS 1 – announced on 2011-03-15

Amount awarded
618 800 PLN
Project start date
2011-12-06
Project end date
2015-12-05
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Inkubator z przepływem CO2 firmy Binder CB 210. Cost: 55 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma

    Authors:
    Janecki DM, Sajek M, Smialek MJ, Kotecki M, Ginter-Matuszewska B, Kuczynska B, Spik A, Kolanowski T, Kitazawa R, Kurpisz M, Jaruzelska J
    Academic press:
    Oncotarget (year: 2018, volume: Vol. 9 (No. 65), pages: 32466-32477), Publisher: Oncotarget
    Status:
    Published
    DOI:
    10.18632/oncotarget.25977 – link to the publication
  2. PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues

    Authors:
    Sajek M, Janecki DM, Smialek MJ, Ginter-Matuszewska B, Spik A, Oczkowski S, Ilaslan E, Kusz-Zamelczyk K, Kotecki M, Blazewicz J, Jaruzelska J
    Academic press:
    Cellular and Molecular Life Sciences (year: 2018, volume: Epub, pages: Epub ahead of print), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s00018-018-2926-5 – link to the publication

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Graphic design and implementation: Jakub Piotrowski