Projects funded by the NCN
Posttranscriptional control of putative cell cycle regulators SIAH1, SPINDLIN3 and TSC22D1 by PUMILIO2 protein in the human seminoma model
2011/01/B/NZ2/04833
Keywords:
germ cells testis germ cell tumor translational regulation
Descriptors:
- NZ1_1: Molecular biology
- NZ1_5: Genetic engineering
- NZ1_2: Biochemistry
Panel:
NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution :
Instytut Genetyki Człowieka PAN
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 1 - announced on 2011-03-15
Amount awarded: 618 800 PLN
Project start date (Y-m-d): 2011-12-06
Project end date (Y-m-d): 2015-12-05
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Inkubator z przepływem CO2 firmy Binder CB 210 (55 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminomaAuthors:Janecki DM, Sajek M, Smialek MJ, Kotecki M, Ginter-Matuszewska B, Kuczynska B, Spik A, Kolanowski T, Kitazawa R, Kurpisz M, Jaruzelska JAcademic press:Oncotarget (rok: 2018, tom: Vol. 9 (No. 65), strony: 32466-32477), Wydawca: OncotargetStatus:PublishedDOI:10.18632/oncotarget.25977 - link to the publication
- PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paraloguesAuthors:Sajek M, Janecki DM, Smialek MJ, Ginter-Matuszewska B, Spik A, Oczkowski S, Ilaslan E, Kusz-Zamelczyk K, Kotecki M, Blazewicz J, Jaruzelska JAcademic press:Cellular and Molecular Life Sciences (rok: 2018, tom: Epub, strony: Epub ahead of print), Wydawca: Springer NatureStatus:PublishedDOI:10.1007/s00018-018-2926-5 - link to the publication