Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Bone tissue engineering with human mesenchymal stem cells, bone morphogenetic proteins, bioactive scaffolds and dynamic culture conditions

2011/01/B/NZ4/00664

Keywords:

Bone marrow mesenchymal stem cells osteogenesis in vitro and in vivo bone morphogenetic proteins bioactive scaffolds perfusion bioreactor

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ1_7: Cell engineering
  • NZ3_1: Cell biology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

UNIWERSYTET JAGIELLOŃSKI

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Osyczka 

Number of co-investigators in the project: 15

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 787 823 PLN

Project start date (Y-m-d): 2011-12-29

Project end date (Y-m-d): 2014-12-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. bioreaktor z wyposażeniem (184 623 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Osteoinductive activity of insulin-functionalized cell culture surfaces obtained using diazonium chemistry
    Authors:
    A. Mikulska, J. Filipowska, A.M. Osyczka, M. Nowakowska, K. Szczubiałka
    Academic press:
    Frontiers in Chemistry, Medicinal and Pharmaceutical Chemistry (rok: 2015, tom: 2, strony: article 117), Wydawca: www.frontiersin.org
    Status:
    Published
    DOI:
    10.3389/fchem.2014.00117 - link to the publication
  2. Wpływ podłoży i rusztowań zawierających krzem lub jego związki na osteogenezę in vitro mezenchymalnych komórek macierzystych i komórek osteoprogenitorowych.
    Authors:
    Derus N, Filipowska J, Osyczka AM.
    Academic press:
    Postępy Biologii Komórki (rok: 2012, tom: 39, strony: 503-518), Wydawca: Polskie Towarzystwo Astronomiczne, Polskie Towarzystwa BIologii KOmórki oraz Fundacja Biologii Komórki i Biologii Molekularnej
    Status:
    Published
  3. Bioactivity of coatings formed on Ti–13Nb–13Zr alloy using plasma electrolytic oxidation
    Authors:
    Maciej Sowa, Magdalena Piotrowska, Magdalena Widziołek, Grzegorz Dercz, Grzegorz Tylko, Tadeusz Gorewoda, Anna M. Osyczka, Wojciech Simka
    Academic press:
    Materials Science and Engineering C (rok: 2015, tom: 49, strony: 159–173), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.msec.2014.12.073 - link to the publication
  4. Characterisation of bioactive films on ti-6Al-4V alloy
    Authors:
    Krzakała A, Słuzalska K, Dercz G, Maciej A, Kazek A, Szade J, Winiarski A, Dudek M, Michalska J, Tylko G, Osyczka AM, Simka W
    Academic press:
    Electrochim Acta (rok: 2013, tom: 104, strony: 425– 438), Wydawca: Elsevier Ltd.
    Status:
    Published
    DOI:
    j.electacta.2012.12.081 - link to the publication
  5. Formation of bioactive coatings on a ti-6Al-7Nb alloy by plasma electrolytic oxidation
    Authors:
    . Krzakała A, Słuzalska K, Widziołek M, Szade J, Winiarski A, Dercz G, Kazek A, Tylko G, Michalska J, Iwaniak A, Osyczka AM, Simka W.
    Academic press:
    Electrochim Acta (rok: 2013, tom: 104, strony: 407-424), Wydawca: Elsevier Ltd.
    Status:
    Published
    DOI:
    j.electacta.2012.07.075 - link to the publication
  6. Incorporation of sol–gel bioactive glass into PLGA improves mechanical properties and bioactivity of composite scaffolds and results in their osteoinductive properties
    Authors:
    J Filipowska, J Pawlik, K Cholewa-Kowalska, G Tylko, E Pamula, L Niedzwiedzki, M Szuta, M Laczka and A M Osyczka
    Academic press:
    Biomedical Materials (rok: 2014, tom: 9, strony: 65001), Wydawca: IOP Publishing Ltd
    Status:
    Published
    DOI:
    10.1088/1748-6041/9/6/065001 - link to the publication
  7. Photocrosslinked ultrathin anionic polysaccharide supports for accelerated growth of human mesenchymal stem cells
    Authors:
    A. Mikulska, J. Filipowska, A. M. Osyczka, M. Szuwarzynski, M. Nowakowska and K. Szczubiałka
    Academic press:
    Cell Proliferation (rok: 2014, tom: 47, strony: 516-526), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/cpr.12118 - link to the publication
  8. New sol-gel bioactive glass and titania composites with enhanced physico-chemical and biological properties
    Authors:
    Pawlik J, Widziołek M, Cholewa-Kowalska K, Laczka M, Osyczka AM
    Academic press:
    J Biomed Mater Res Part A (rok: 2013, tom: 00A, strony: 000-000), Wydawca: John Wiley & Sons, Inc.
    Status:
    Published
    DOI:
    10.1002/jbm.a.34903 - link to the publication