Projects funded by the NCN
The new benzanilide derivates as promising anticancer agents
2011/01/B/NZ4/03499
Keywords:
Benzanilide derivates Anticancer activity Apoptosis Reactive oxygen species Ribonucleotide Reductase Lung Cancer
Descriptors:
- NZ4_16:
- NZ4_11: Metabolism
- NZ4_17:
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny
woj. wielkopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: OPUS 1 - announced on 2011-03-15
Amount awarded: 356 200 PLN
Project start date (Y-m-d): 2011-12-16
Project end date (Y-m-d): 2015-09-15
Project duration:: 45 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- wirówka z wyposażeniem (30 000 PLN)
- Inkubator CO2 (34 000 PLN)
- komora laminarna (30 000 PLN)
Information in the final report
- Publication in academic press/journals (3)
- Selective anticancer activity of the novel thiobenzanilide 63T against human lung adenocarcinoma cellsAuthors:Malgorzata Kucinska, Hanna Piotrowska, Natalia Lisiak, Mariusz Kaczmarek, Hanna Dams-Kozlowska, Walter H Granig, Martina Höferl, Walter Jäger, Martin Zehl, Marek Murias, Thomas ErkerAcademic press:Toxicology in Vitro (rok: 2016, tom: 37, strony: 148-161), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.tiv.2016.09.017 - link to the publication
- The role of oxidative stress in the 63T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell line CCD39Lu cell lineAuthors:Malgorzata Kucinska, Helena Mieszczak, Hanna Piotrowska, Mariusz Kaczmarek, Walter Granig, Marek Murias, Thomas ErkerAcademic press:Chemico-Biological Interactions (tom: nie dotyczy, strony: nie dotyczy), Wydawca: ElsevierStatus:SubmittedDOI:nie - link to the publication
- Novel promising estrogenic receptor modulators: cytotoxic and estrogenic activity of benzanilides and dithiobenzanilidesAuthors:Malgorzata Kucinska, Maria-Dolores Giron, Hanna Piotrowska, Natalia Lisiak, Walter Granig, Francisco-Javier Lopez-Jaramillo, Rafael Salto, Marek Murias, Thomas ErkerAcademic press:PloSOne (rok: 2016, tom: 2016, strony: 45307), Wydawca: PloSOneStatus:PublishedDOI:10.1371/journal.pone.0145615 - link to the publication