Proteomic and genetic analysis of the role of the EnvZ/OmpR pathway of Yersinia enterocolitica in the regulation of virulence properties and adaptation to stress conditions
2011/01/B/NZ6/01845
Keywords
Descriptors
- NZ6_4: Bakteriologia
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Uniwersytet Warszawski, Wydział Biologii
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 1 – announced on 2011-03-15
- Amount awarded
- 399 900 PLN
- Project start date
- 2011-12-13
- Project end date
- 2014-12-12
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Przystawka do fluorymetru (czytnik Infinite M200 PRO). Cost: 10 000 PLN
- Termocykler firmy BioRad (PTC-1148) (2 pcs). Cost: 30 000 PLN
- Zestaw do elektroforezy agarozowej wraz z zasilaczem BioRad (164-0300 MiniSub Cell/Power Pac Basic System). Cost: 5 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
Regulatory protein OmpR influences the serum resistance of Yersinia enterocolitica O:9 by modifying the structure of the outer membrane
- Authors:
- Skorek K., Raczkowska A., Dudek B., Miętka K., Guz-Regner K., Pawlak A., Klausa E., Bugla-Płoskońska K., Brzostek K
- Academic press:
- PLOS ONE (year: 2013, volume: 8(11): e79525, pages: 46040), Publisher: Public Library of Science
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0079525 – link to the publication
-
Impact of OmpR on the membrane proteome of Yersinia enterocolitica in different environments: repression of major adhesin YadA and heme receptor HemR
- Authors:
- Marta Nieckarz, Adrianna Raczkowska, Janusz Dębski, Michał Kistowski, Michał Dadlez, Jürgen Heesemann, Ombeline Rossier, Katarzyna Brzostek
- Academic press:
- Environmental Microbiology (year: 2016, volume: 1, pages: 25), Publisher: Society for Applied Microbiology and John Wiley & Sons Ltd
- Status:
- Published
- DOI:
- 10.1111/1462-2920.13165 – link to the publication
-
Expression of the AcrAB components of the AcrAB-TolC multidrug efflux pump of Yersinia enterocolitica is subject to dual regulation by OmpR
- Authors:
- Adrianna Raczkowska, Joanna Trzos, Olga Lewandowska, Marta Nieckarz, Katarzyna Brzostek
- Status:
- Accepted for publication
Articles in post-conference publications (2)
-
OmpR-dependent variations in the susceptibility of Yersinia enterocolitica O9 to the bactericidal activity of serum involves modification of the proteins and lipopolysaccharide content of the outer membrane
- Authors:
- 19.Skorek, K. Raczkowska A., Dudek B., Bugla-Płoskońska G., Brzostek K.
- Conference:
- Yersinia 11: The 11th International symposium on Yersinia. (year: 2013, pages: 47), Publisher: Cold Spring Harbor Laboratory
- Date:
- conference 24-28 czerwiec
- Status:
- Published
-
Poszukiwanie genów regulonu OmpR Yersinia enterocolitica O:9 metodą mutagenezy transpozonowej
- Authors:
- Skorek Karolina, Raczkowska Adrianna, Brzostek Katarzyna
- Conference:
- XXVII Zjazd Polskiego Towarzystwa Mikrobiologów w Lublinie Drobnoustroje bez granic (year: 2012, pages: P-I-007), Publisher: Polskie Towarzystwo Mikrobiologów
- Date:
- conference 5-8 wrzesień
- Status:
- Published