Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Applications of atomic force microscopy in nanomedicine

2011/01/M/ST3/00711

Keywords:

atomic force microscopy living cell elasticity identification of canceorus cells

Descriptors:

  • NZ4_11: Metabolism
  • NZ1_3: Biophysics

Panel:

ST3 - Condensed matter physics: structure, electronic properties, fluids, nanosciences, biological physics

Host institution :

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Małgorzata Lekka 

Number of co-investigators in the project: 6

Call: HARMONIA 1 - announced on 2011-03-15

Amount awarded: 575 400 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2014-11-30

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator z płaszcem wodnym CO2 (40 000 PLN)
  2. komputer z monotorem i dyskiem NAS (5 000 PLN)
  3. Wirówka typu eppedorf (4 000 PLN)
  4. zestaw do elektroforezy - aparat do eketroforezy z zestawem do transferu i zasilaczem (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Nano‑characterization of two closely related melanoma cell lines with different metastatic potential
    Authors:
    J Gostek, Sz.Prauzner–Bechcicki, B.Nimmervoll, K Mayr, J.Szlagor, P.Hinterdorfer, L.A.Chtcheglova, M.Lekka
    Academic press:
    European Biophysics Journal (rok: 2015, ), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00249-014-1000-y - link to the publication
  2. Reaction pathway and free energy profile determined for specific recognition of oligosaccharide moiety of carboxypeptidase Y
    Authors:
    E.Senkara-Barwijuk, T. Kobiela, K. Lebed, M. Lekka
    Academic press:
    Biosensors and Bioelectronics (rok: 2012, tom: 36, strony: 103-109), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2012.04.014 - link to the publication
  3. Standardized Atomic Force Microscopy method for measuring mechanical properties of soft samples: the Dubrovnik procedure
    Authors:
    J.Schäpe, T.Luque, H.Doschke, H.Schillers, M.Wälte, J.José Uriarte, N.Campillo, G.P.Michanetzis, J.Gostek, A.Dumitru, E.Herruzo, P.Parot, M.Galluzzi, A.Podestà, S.Scheuring, Y.Missirlis, R.Garcia, M.Odorico, M.Lekka, F. Rico, J.-L.Pellequer, H.Oberleithne, D.Navajas, M.Radmacher
    Academic press:
    PLOS One (rok: 2015, tom: -, strony: -), Wydawca: PLOS
    Status:
    Submitted
  4. The softening of human bladder cancer cells happens at an early stage of the malignancy process
    Authors:
    Jorge R. Ramos, Joanna Szlagor, Ricardo Garcia, Malgorzata Lekka
    Academic press:
    Beilstein Journal of Nanotechnology (rok: 2014, tom: 5, strony: 447-457), Wydawca: Beilstein-Institut
    Status:
    Published
    DOI:
    10.3762/bjnano.5.52 - link to the publication