Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Synthesis and marking the activity of new potential antagonists of receptors for excitatory amino acids which have the structure of aromatic amides derived from heterocyclic acids and having anti-convulsive effect.

2011/01/B/NZ4/01065

Keywords:

anticonvulsant activity neurotoxicity time of action synthesis excitatory amino acids.

Descriptors:

  • NZ4_16:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Aleksander Mazurek 

Number of co-investigators in the project: 4

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 169 260 PLN

Project start date (Y-m-d): 2011-12-15

Project end date (Y-m-d): 2014-12-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Próżniowa wyparka rotacyjna ROTAVAPOR® R-210/V Advanced, firmy Buchi Labortechnik AG (60 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. SYNTHESIS AND STUDY OF SUBSTITUTED AMIDES OF ISOQUINOLINE-3- AND ISOQUINOLINE-1-CARBOXYLIC ACIDS AS POTENTIAL ANTICONVULSANTS
    Authors:
    Marzanna Strupińska, Grażyna Rostafińska-Suchar, Bartłomiej Jakubowicz, Paulina Klimkiewicz, Ewelina Lal, Mateusz Oczkowski, Ewa Próchniak, Elżbieta Pirianowicz-Chaber, Aleksander P. Mazurek
    Academic press:
    ACTA POLONIAE PHARMACEUTICA-DRUG RESEARCH (rok: 2017, tom: 74 N0. 4, strony: 1111-1118), Wydawca: POLISH PHARMACEUTICAL SOCIETY
    Status:
    Published
    DOI:
    Brak - link to the publication
  2. SYNTHESIS AND STUDY OF HALOGENATED BENZYLAMIDES OF SOME ISOCYCLIC AND HETEROCYCLIC ACIDS AS POTENTIAL ANTICONVULSANTS
    Authors:
    MARZANNA STRUPIŃSKA, GRAŻYNA ROSTAFIŃSKA-SUCHAR, ELŻBIETA PIRIANOWICZ-CHABER, MATEUSZ GRABCZUK, MAGDALENA JÓZWENKO, HUBERT KOWALCZYK, JOANNA SZUBA, MONIKA WÓJCICKA, TRACY CHEN, and ALEKSANDER P. MAZUREK
    Academic press:
    ACTA POLONIAE PHARMACEUTICA-DRUG RESEARCH (rok: 2015, tom: 72 No. 3, strony: 489-496), Wydawca: POLISH PHARMACEUTICAL SOCIETY
    Status:
    Published
    DOI:
    brak - link to the publication
  3. Synthesis and study of substituted amides of some 5-membered isocyclic and heterocyclic acids as potential anticonvulsants
    Authors:
    Marzanna Strupińska, Bartłomiej Jakubowicz, Grażyna Rostafińska-Suchar, Elżbieta Pirianowicz-Chaber, Magdalena Konarowska, Aleksander P. Mazurek
    Academic press:
    ACTA POLONIAE PHARMACEUTICA-DRUG RESEARCH , Wydawca: POLISH PHARMACEUTICAL SOCIETY
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  4. SYNTHESIS AND RESEARCH OF BENZYLAMIDES OF SOME ISOCYCLIC AND HETEROCYCLIC ACIDS AS POTENTIAL ANTICONVULSANTS
    Authors:
    MARZANNA STRUPIŃSKA, GRAŻYNA ROSTAFIŃSKA-SUCHAR, ELŻBIETA PIRIANOWICZ- CHABER, JAMES P. STABLES, JEFF JIANG and RYSZARD PARUSZEWSKI
    Academic press:
    ACTA POLONIAE PHARMACEUTICA-DRUG RESEARCH (rok: 2013, tom: 70 No. 4, strony: 681-686), Wydawca: POLISH PHARMACEUTICAL SOCIETY
    Status:
    Published
    DOI:
    BRAK - link to the publication

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