Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Porphyromonas gingivalis: natural defense and regulatory mechanisms

2011/01/D/NZ6/00269

Keywords:

CRISPR Porphyromonas gingivalis crRNA

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ3_1: Cell biology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Krzysztof Pyrć 

Number of co-investigators in the project: 5

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 999 212 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2016-11-30

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw kolumn do systemu chromatografii cieczowej. (16 500 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage.
    Authors:
    Pyrc K, Milewska A, Kantyka T, Sroka A, Maresz K, Kozieł J, Nguyen KA, Enghild JJ, Knudsen AD, Potempa J.
    Academic press:
    Infection and immunity (rok: 2012, tom: 81, strony: 55-64), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/IAI.00830-12 - link to the publication
  2. crRNAs in Porphyromonas gingivalis CRISPR-Cas I‑C system.
    Authors:
    Burmistrz M, Rodriguez Martinez JI, Staniec D, PyrcK
    Academic press:
    FEBS OpenBio (rok: 2017, tom: -, strony: -), Wydawca: Federation of European Biochemical Societies
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. CRISPR-Cas Systems in Prokaryotes.
    Authors:
    Burmistrz M, Pyrć K
    Academic press:
    Polish journal of microbiology (rok: 2015, tom: 64, strony: 193-202), Wydawca: Polskie Towarzystwo Mikrobiologów
    Status:
    Published
    DOI:
    brak - link to the publication
  4. Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis.
    Authors:
    Benedyk M, Mydel PM, Delaleu N, Płaza K, Gawron K, Milewska A, Maresz K, Koziel J, Pyrc K, Potempa J.
    Academic press:
    Journal of innate immunity (rok: 2015, tom: -, strony: -), Wydawca: Karger
    Status:
    Published
    DOI:
    10.1159/000441724 - link to the publication
  5. Staphylococcus aureusProteases Degrade Lung Surfactant Protein A Potentially impairing Innate Immunity of the Lung
    Authors:
    Tomasz Kantyka, Krzysztof Pyrc, Milosz Gruca, Jan Smagur, Karolina Plaza, Krzysztof Guzik, Slawomir Zeglen, Marek Ochman, Jan Potempa
    Academic press:
    Journal of Innate Immunity (rok: 2013, tom: 5, strony: 251-260), Wydawca: Karger AG
    Status:
    Published
    DOI:
    10.1159/000345417 - link to the publication
  6. Bacterial Proteases in Disease – Role in Intracellular Survival, Evasion of Coagulation/Fibrinolysis Innate Defenses, Toxicoses and Viral Infections.
    Authors:
    Grzegorz Dubin, Joanna Kozieł, Krzysztof Pyrć, Benedykt Władyka, Jan Potempa
    Academic press:
    Current Pharmaceutical Design (rok: 2013, tom: 19, strony: 1090-1113), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/1381612811319060011 - link to the publication
  7. Type III CRISPR complexes from Thermus thermophilus.
    Authors:
    Szychowska M, Siwek W, Pawolski D, Kazrani AA, Pyrc K, Bochtler M
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63, strony: 377-386), Wydawca: Polska Akademia Nauk Komitet Biochemiczny
    Status:
    Published
    DOI:
    10.18388/abp.2016_1261 - link to the publication
  8. Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems.
    Authors:
    Burmistrz M, Dudek B, Staniec D, Rodriguez Martinez JI, Bochtler M, Potempa J, Pyrc K.
    Academic press:
    Journal of Bacteriology (rok: 2015, tom: 197, strony: 2631-2641), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/JB.00261-15 - link to the publication

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