Projects funded by the NCN

Investigation of the role of strigolactones in response to drought using a barley mutant collection

Call: BEETHOVEN LIFE 1 , Panel: NZ2

Principal investigator: dr Marek Marzec

UNIWERSYTET ŚLĄSKI, Wydział Biologii i Ochrony Środowiska

How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

Call: SONATINA 3 , Panel: NZ2

Principal investigator: dr Tomasz M. Kuliński

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Analysis of the role of cytoplasmic polyadenylation in the regulation of the innate immune response

Call: OPUS 17 , Panel: NZ2

Principal investigator: prof. Andrzej Stanisław Dziembowski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Functional genomic analysis of Staphylococcus aureus Kayvirus genus phages in a search for molecular basis of wide host-...

Call: OPUS 17 , Panel: NZ2

Principal investigator: dr hab. Małgorzata Barbara Łobocka

Instytut Biochemii i Biofizyki PAN

Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

Call: OPUS 17 , Panel: NZ2

Principal investigator: dr Mateusz Kurciński

Uniwersytet Warszawski

Life at the limits: diversity, adaptation strategies and bioprospecting of microbes living in Arctic deep sea habitats

Call: GRIEG 1 , Panel: NZ2

Principal investigator: prof. Tadeusz Kaczorowski

Uniwersytet Gdański, Wydział Biologii

Genetic modifiers in Niemann-Pick type C disease.

Call: PRELUDIUM 18 , Panel: NZ2

Principal investigator: Dominika Emilia Sitarska

Instytut Psychiatrii i Neurologii

Elucidation of the mechanisms that induce copy number polymorphism of large genome fragments and of the relations betwee...

Call: OPUS 7 , Panel: NZ2

Principal investigator: prof. Marek Marian Figlerowicz

Instytut Chemii Bioorganicznej PAN

Identification of new genes of high risk for melanoma in the Polish population by next-generation sequencing

Call: OPUS 7 , Panel: NZ2

Principal investigator: prof. Tadeusz Dębniak

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarsko-Biotechnologiczny i Medycyny Laboratoryjnej

Comparizon of functional interdependence between AMPK pathway controlling energy homeostasis and SWI/SNF-type chromatin ...

Call: OPUS 7 , Panel: NZ2

Principal investigator: dr hab. Tomasz Jacek Sarnowski

Instytut Biochemii i Biofizyki PAN

Identification of miRNAs involved in classical Hodgkin lymphoma pathogenesis using combined expression and mutation prof...

Call: HARMONIA 6 , Panel: NZ2

Principal investigator: dr hab. Maciej Witold Giefing

Instytut Genetyki Człowieka PAN

Leber Hereditary Optic Neuropathy -why are not all men (and women) created equal?

Call: OPUS 8 , Panel: NZ2

Principal investigator: prof. Ewa Maria Bartnik

Uniwersytet Warszawski, Wydział Biologii

Three dimensional (3D) visualization of immediate-early genes (IEGs) structure upon activation, using a novel technique:...

Call: PRELUDIUM 8 , Panel: NZ2

Principal investigator: Paweł Maciej Trzaskoma

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Analysis of the regulatory sequences in the SPAST gene and the influence of these sequences changes to transcriptional a...

Call: PRELUDIUM 8 , Panel: NZ2

Principal investigator: dr Ewelina Elert-Dobkowska

Instytut Psychiatrii i Neurologii

Obliczeniowy model specyficznej tkankowo regulacji genów.

Call: ETIUDA 3 , Panel: NZ2

Principal investigator: Paweł Bednarz

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Reconstructing cardiovascular cell lineage evolution, one cell at a time

Call: OPUS 18 , Panel: NZ2

Principal investigator: dr hab. Cecilia Lanny Winata

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Mechanism of regulation glycosaminoglycan levels by resveratrol in a mouse model of a neuronopathic disease from the muc...

Call: PRELUDIUM 18 , Panel: NZ2

Principal investigator: Estera Elmira Rintz

Uniwersytet Gdański, Wydział Biologii

High-resolution analysis of data from proton-deuterium exchange experiments monitored by mass spectrometry.

Call: PRELUDIUM BIS 1 , Panel: NZ2

Principal investigator: prof. Michał Lech Dadlez

Instytut Biochemii i Biofizyki PAN

Towards automatic derivation of geometry-based descriptors as surrogates for complex structural approaches in enzyme-sub...

Call: PRELUDIUM 19 , Panel: NZ2

Principal investigator: Carlos Eduardo Sequeiros Borja

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Unraveling the influence of posttranscriptional modifications on RNA 3D structure formation and its dynamics, with the i...

Call: OPUS 19 , Panel: NZ2

Principal investigator: prof. Janusz Marek Bujnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Cytogenetic and molecular analyses of positioning of human sperm chromosomes, including: sperm chromatin integrity, epig...

Call: SONATA BIS 10 , Panel: NZ2

Principal investigator: dr hab. Marta Anna Olszewska

Instytut Genetyki Człowieka PAN

Discovery and characterization of RNA structure motifs conserved in positive-sense single-stranded RNA viruses and in ot...

Call: SONATA 16 , Panel: NZ2

Principal investigator: dr Tomasz Krzysztof Wirecki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

RecHybrid: Regulation of meiotic recombination in Arabidopsis and tomato hybrids by MutS-dependent sensitivity to geneti...

Call: OPUS 20 (LAP) , Panel: NZ2

Principal investigator: dr hab. Piotr Andrzej Ziółkowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Unraveling the genetic basis of crossover variation in Arabidopsis thaliana by exploiting a broad diversity

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr Alexandre Pelé

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: dr Magdalena Dąbrowska

Instytut Chemii Bioorganicznej PAN

BCOR alterations and the activation of CXCL12 oncogenic pathway in classical Hodgkin lymphoma

Call: OPUS 21 , Panel: NZ2

Principal investigator: prof. Maciej Witold Giefing

Instytut Genetyki Człowieka PAN

Investigating the hotspot competition between three adjacent recombination hotspots in response to different types of po...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Maja Magdalena Szymańska-Lejman

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Mechanisms of cell cycle regulation in Pseudomonas aeruginosa and theirrole in adaptation capacity of the dangerous path...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Aneta Urszula Szulc

Uniwersytet Gdański, Wydział Biologii

Understanding the biophysical limiting factors of patterning precision in developing tissues

Call: SONATA BIS 11 , Panel: NZ2

Principal investigator: dr Marcin Paweł Zagórski

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Identification and analysis of mechanisms controlling steady-state levels and quality of mitochondrial mRNA

Call: SONATA BIS 11 , Panel: NZ2

Principal investigator: dr hab. Roman Józef Szczęsny

Instytut Biochemii i Biofizyki PAN

CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

Call: SONATA 17 , Panel: NZ2

Principal investigator: dr Adam Kawałek

Instytut Biochemii i Biofizyki PAN

The role and physical properties of the 3-dimensional chromatin structure in the differentiation of hematopoietic cells ...

Call: PRELUDIUM BIS 3 , Panel: NZ2

Principal investigator: dr hab. Jakub Karol Mieczkowski

Gdański Uniwersytet Medyczny, Międzynarodowa Agenda Badawcza

Mathematical modeling of micro-RNA control of transcript levels and translation efficiency in irradiated cells

Call: OPUS 23 , Panel: NZ2

Principal investigator: prof. Marek Kimmel

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Molecular Mechanisms of Dietary Intervention on Neurodegeneration

Call: JPND Call 2022 , Panel: NZ2

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo...

Call: JPND Call 2022 , Panel: NZ2

Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

Uniwersytet Warszawski

Comprehensive, multimodal profiling of chromatin states and gene expression in single cells.

Call: SONATA BIS 12 , Panel: NZ2

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

The influence of disturbance of the cell envelope homeostasis on the expression of the Sec translocon components in Heli...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Patrycja Ambroziak

Uniwersytet Gdański, Wydział Biologii

Synthetic biology approach to biosynthesis of termophilic, problematic and toxicprotein: bacteriophage expression system...

Call: OPUS 25 , Panel: NZ2

Principal investigator: prof. Piotr Mariusz Skowron

Uniwersytet Gdański, Wydział Chemii

Are phage introns a gap in our knowledge?

Call: SONATA BIS 13 , Panel: NZ2

Principal investigator: dr Jakub Barylski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Advanced statistical and deep learning models to predict cancer risk and support treatment decisions

Call: SONATA BIS 13 , Panel: NZ2

Principal investigator: dr Michał Marczyk

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Passive regulation of gene expression

Call: OPUS 26 (LAP) , Panel: NZ2

Principal investigator: dr Tomasz Wojciech Turowski

Instytut Biochemii i Biofizyki PAN

Unravelling the conservation of crossover hotspots and regulation of meiotic recombination at the pericentromeres

Call: SONATINA 8 , Panel: NZ2

Principal investigator: dr Maja Magdalena Szymańska-Lejman

Instytut Chemii Bioorganicznej PAN

Analysis of extracellular vesicles isolated from perfusion fluid as potential biomarkers of kidney quality from deceased...

Call: PRELUDIUM 23 , Panel: NZ2

Principal investigator: Maksymilian Baryła

Warszawski Uniwersytet Medyczny

RIBO-ICE: Ribosomes and Translation. Protein biosynthesis in cold, a study of Antarctic bacteria.

Call: OPUS 27 , Panel: NZ2

Principal investigator: dr hab. Agata Lucyna Starosta

Instytut Biochemii i Biofizyki PAN

Using ALTERNA to resolve the causality dilemma between RNA multiple sequence alignment and RNA secondary structure

Call: OPUS 27 , Panel: NZ2

Principal investigator: dr Evgenii Baulin

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Role of LTR-driven circTNFRSF11A in the pathogenesis of classic Hodgkin lymphoma (cHL)

Call: PRELUDIUM 23 , Panel: NZ2

Principal investigator: Greta Nella Sawicz

Instytut Genetyki Człowieka PAN

U1-united: Deconstructing non-canonical functions of U1 snRNP in Arabidopsis thaliana

Call: OPUS 28 , Panel: NZ2

Principal investigator: prof. Artur Michał Jarmołowski

Uniwersytet im. Adama Mickiewicza w Poznaniu

The complex nature of multidomain proteins: the unmasked activity of human Dicer ribonuclease – expect the unexpected

Call: OPUS 28 , Panel: NZ2

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Decoding the role and activation signal of SitKR, a novel developmental two-component system, in regulation of gene expr...

Call: PRELUDIUM 24 , Panel: NZ2

Principal investigator: Patrycja Weronika Wadach

Uniwersytet Wrocławski

Mechanisms of IFIT autoregulation and their functional significance

Call: PRELUDIUM 24 , Panel: NZ2

Principal investigator: Jakub Józef Kowalski

Uniwersytet Warszawski